Yes, it can be done, but injecting pills is generally unadvisable, especially in this instance as the majority of these pills are inert binders, fillers and some kind of NSAID like APAP or Ibuprofen. The safest way to to this would be to perform a Cold Water Extraction on all of the pills you have. Let the excess water dissolve. You can speed the process by introducing heat of some kind, but always keep it relatively low.
You will be left with a solution of essentially just Oxycodone and water and a miniscule amount of the other stuff. This will be much safer and easier on your body then say, putting the pill directly in a spoon and trying to shoot it just like one would a 30mg Oxycodone.