New ketamine study with interesting implications

[vortech]

http://www.nature.com/news/sex-matters-in-experiments-on-party-drug-in-mice-1.23022

Anyone make sense of how this is possible? I dont doubt there is some sort of connection with the olfactory system since I'm always going on about awesome smells when I get the best effects from any arylcyclohexylamines. Any insight is appreciated!

 

[vortech]

A study with similar findings https://arstechnica.com/science/201...-less-pain-when-male-lab-workers-are-present/

Seems to be maybe pheromones? And does this translate in any capacity to humans?

 

[Jabberwocky]

What a bizarre finding. There's a lot of fundamental science based on mouse models that could be called into question based on this. I doubt it carries over to humans since I don't think there is a stress response to male scent within humans; it'd be surprising if there was as it'd be anti-adaptive. It's funny to imagine a world where taking bumps of K off a mans armpit is the recommended way to treat depression with ketamine. Just speculating but perhaps in certain subsets of the population like traumatized females male scent can become a trigger for stress and then maybe a similar effect could be observed?

 

[vortech]

The study is also implying that unstressed mice don't receive anl noticeable antidepressant effect from ketamine. That bit might translate to humans to a degree.