PharmaTrain
Bluelighter
- Joined
- Jul 8, 2022
- Messages
- 279
So we all know not all generics are equal. I have tried all Clonazapam generics and even brand name. The Teva brand always worked best for me and lasted the longest besides Brand name. Now without notice CVS has switched manufacturers to Advagen Pharmaceuticals (Indian) company. So since I had these once before, I excepted them due to the new rules that I would have to contact the doctor to write a new script saying "dispense Teva brand only". This is when I ran out keep in mind. Now I researched into the chemical composition of this type of Clonazapam and to my surprise it's a new designer drug made differently besides inactive ingredients. Lets take a look at the difference in these 2 generics:
glycol, microcrystalline cellulose, croscarmellose sodium and magnesium stearate, with the following colourants: 0.5 mg-FD & C Yellow 6 Al Lake, D & C Yellow 10 Al Lake; 1 mg-FD & C Blue 1 Al lake and FD & C Blue 2 Al lake
Chemically, clonazepam is 5-(2-chlorophenyl)-1,3-dihydro-7-nitro- 2H -1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has a molecular weight of 315.72 and the following structural formula:
That was Alvagen. Now look at the 5 formulas Chemically:
www.ncbi.nlm.nih.gov
This shows that the name on the bottle called Clonazepam is not what were used to with Teva chemically speaking but a crude cheap novel designer knock off without proper testing backed by trials long term on humans. One the first link you'll see the 5 formulas and the 2 which have been on the books since 1971. The other 3 are applied patents pending. Now look at the Teva generic formula:
Chemically, clonazepam, USP is 5-(o -chlorophenyl)-1,3-dihydro-7-nitro-2H -1,4-benzodiazepin-2-one. It is a light yellow crystalline powder.
IF you have looked at the 2 formulas and used the links provided , you'll see the difference and the risks of these new untested designer drugs using research chemicals and saying it's Clonazepam when it should be labeled "Clonitrazolam". Your pharmacist won't tell you this even if they know. They are putting sneaky Pete in our meds without notice. On Reddit concerning this Advagen clonazepam most people hate it due to lack of potency and they say it doesn't last. I took 1 tablet to see and it was strong at first but dropped off quickly. It lingers but not like the Teva's.
Since these pharmacies are keeping patients in the dark like CVS , I'm going to get the brand name Clonazepam which is the same formula since 1971. This is why going with the brand name is more trusted than these generic companies. Also no more CVS. They have pulled this swiching of preferred generics too many times. I undershand there are shortages but not the TEVA Clonazepam 1 or 2 mg tablets. If we can't trust a pharmacy to be honest we should not be taking anything from them. If they are ignorant of what's going on they shoulf not have that job. We need to hold these places accountable especially at the local level. THIS IS WHERE CHANGE STARTS. I TELL YOU THE TRUTH.
DESCRIPTION
Clonazepam Tablets, USP, a benzodiazepine, is available as scored tablet with debossing Λ containing 0.5 mg of clonazepam and unscored tablets with debossing Λ and Λ containing 1 mg or 2 mg of clonazepam respectively. Each tablet also contains lactose monohydrate, polyethylene 66 67 69glycol, microcrystalline cellulose, croscarmellose sodium and magnesium stearate, with the following colourants: 0.5 mg-FD & C Yellow 6 Al Lake, D & C Yellow 10 Al Lake; 1 mg-FD & C Blue 1 Al lake and FD & C Blue 2 Al lake
Chemically, clonazepam is 5-(2-chlorophenyl)-1,3-dihydro-7-nitro- 2H -1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has a molecular weight of 315.72 and the following structural formula:
That was Alvagen. Now look at the 5 formulas Chemically:
‘New/Designer Benzodiazepines’: An Analysis of the Literature and Psychonauts’ Trip Reports
NPS belonging to the benzodiazepine (BZD) class, e.g., ‘legal/designer BZDs’/‘research chemicals’, have recently emerged in the drug (mainly online/virtual) market. While certain NPS belonging to the BZD class possess ...
www.ncbi.nlm.nih.gov
DESCRIPTION
Each tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg of clonazepam USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP, 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP, 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake.Chemically, clonazepam, USP is 5-(o -chlorophenyl)-1,3-dihydro-7-nitro-2H -1,4-benzodiazepin-2-one. It is a light yellow crystalline powder.
IF you have looked at the 2 formulas and used the links provided , you'll see the difference and the risks of these new untested designer drugs using research chemicals and saying it's Clonazepam when it should be labeled "Clonitrazolam". Your pharmacist won't tell you this even if they know. They are putting sneaky Pete in our meds without notice. On Reddit concerning this Advagen clonazepam most people hate it due to lack of potency and they say it doesn't last. I took 1 tablet to see and it was strong at first but dropped off quickly. It lingers but not like the Teva's.
Since these pharmacies are keeping patients in the dark like CVS , I'm going to get the brand name Clonazepam which is the same formula since 1971. This is why going with the brand name is more trusted than these generic companies. Also no more CVS. They have pulled this swiching of preferred generics too many times. I undershand there are shortages but not the TEVA Clonazepam 1 or 2 mg tablets. If we can't trust a pharmacy to be honest we should not be taking anything from them. If they are ignorant of what's going on they shoulf not have that job. We need to hold these places accountable especially at the local level. THIS IS WHERE CHANGE STARTS. I TELL YOU THE TRUTH.
