I was a fond smoker of weed for many years and then stopped( along with other more distructive substances). Recently opportunity and curiosity caused me to re evaluate my Cannabis abstinance. However, the outcome was not at all what I expected. Unless this has happened to you it will sound very strange.[I will preface this with the fact that I discovered that I can smoke High thc medical without negative effect after 9 pm. and I have a theory] My journey started with some high cbd/ .3% thc Abacus "flower". I had been using cbd already for over a year and so didnt expect any high from it. Strangely I got an uncomfortable buzz and a really bad headache. As it was legally purchased at a cbd dispensary in a state where pot is not legal... I really wondered why I caught a buzz in the first place. Then one afternoon I take just 2 hits of a high grade medical...For 15 minutes I felt a light lifting...then around the half hour point I was way too high. I could barely move from my chair and I seemed to have lost the ability to swallow or blink..my breathing was loud in my ears. I was inches from a total panic. My past experience(s) taught me how to chill a panic attack but it was a challenge. I could not wait for it to stop and it seemed to last hours. Thinking that two deep bong hits was just too much for my new tolerance level and the high thc of the bud....the next night tried one hit...it was perfect...so I had a few more and then a few more after that...with no issue. Strange but even stranger was the next day...one hit and I was wrecked and anxiety ridden. A week went by and I tried RSO cookies at night. Worked great !! Did that for a week.. Then tried one during the day and had the same intense reaction I had initially with the smoke. AHA...I figured its a medication interaction to something I only used early in the day. So it had to be either the 30mg Prozac or 30 mg Adderall . Adderall more likely as it would be depleted by evening. I started taking just 20mg in the morning and not the 10 at noon and found I could smoke slightly earlier at night. So I would say Addys the culpret. I have tried to research this "Madderall" interaction and there is little reliable info. It appears that a large number of people seek that combo. Let me stress that my experience was mentally/ physically profound !!! I dont care to get into past "drug use"...just know that I am not a newbie. It was not pleasant and my loss of contol was actually dangerous. I know some will probably laugh at my story. Hell...I laugh at it. However, as this is a forum for harm reduction ...I would offer caution to others considering the combo for the first time. Be in a safe place. I would wecome any and all input on this topic.Even if you think my combo theory is wrong. Thanks