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Multiorgan failure after injection of “bath salts” (MDPV)

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http://www.thepoisonreview.com/2012/03/19/multiorgan-failure-after-injection-of-bath-salts-mdpv/

This case report, from the University of Virginia School of Medicine, describes a 25-year-old man who presented to the emergency department with agitation and altered mental status after injecting a “bath salt” product. On arrival he had significant tachycardia (175 bpm) and hyperthermia (106.3oF). He was also combative and had mydriasis. The patient was intubated and cooled with ice packs and cooling blankets.

During his first 2 days in the intensive care unit, the patient developed anuric renal failure requiring dialysis, hepatic failure, disseminated intravascular coagulation (DIC), and rhabdomyolysis.

Urine tested positive for the synthetic cathinone MDPV but was negative for a large number of other hallucinogens, including LSD, mescaline, MDMA (ecstasy), PCP, and psilocin.

The patient was discharged after an 18-day hospital stay, and required hemodialysis for a total of 1 month after exposure.

http://www.thepoisonreview.com/2012/03/19/multiorgan-failure-after-injection-of-bath-salts-mdpv/
 
The authors note that MDPV inhibits re-uptake of dopamine and norepinephrine, but has little effect on serotonin activity. Although little clinical information about this hallucinogen is available, it seems to cause my psychosis and aggression than other stimulants.

I guess they meant to type it seems to cause MORE psychosis and aggression than other stimulants
 
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