ILikeToEatPeople
Greenlighter
- Joined
- Sep 16, 2016
- Messages
- 25
Anyone out there with experience on MS Contin and Opana ER?
If taken normally (i.e orally) what would generally (i.e for most people) work better for pain control between 30mg MS Contin 3 times per day and 20mg Opana ER 2 times per day?
I'm a bit confused because of how low the oral bioavailability of Opana is (oral is barely 10% ). So taking a 20mg Opana ER would ultimately result in ~2mg being the proportion of a it that enters the circulation into the body and is thus able to have an active effect. At such a low bioavailability, wouldn't the MS Contin be better or is Opana/Oxymorphone really THAT strong that it would still be a better option?
The official conversion charts say a 90mg total MS Contin dose per day is equal to 15mg Opana ER twice per day but that doesn't seem to make any sense considering how radically awful the Opana bioavailability is.
I understand that Opana/Oxymorphone is insanely potent at 100% BA (i.e if used intravenously) but if that route isn't even an option (as far as I know Opana ER can't even be prepared for proper IV use due to abuse proofing - correct me if I'm wrong though) it just seems that MS Contin would be the better option.
If you guys had the option to choose between 3 x 30mg MS Contin per day and 2 x 20mg Opana ER per day, what would you select? MS Contin has poor oral BA too but even so, it's higher than 10%.
Also, on a side note... is it actually possible to prepare an Opana ER for IV use with a micron filter? It's my understanding that there is some sort of molecular bond or something in regards to the oxymorphone and time-release mechanism so wouldn't it basically be pointless to use a micron filter? Does anyone know if it's true that there's still some sort of generic Opana ER around than can actually be safely/easily prepared for IV?
Anyways, the main point here is legitimate pain control and the IV stuff is just out of curiosity. If 20mg Opana ER twice per day wouldn't generally cut it compared with 30mg MS Contin three times per day then what dose of Opana ER would cut it?
If taken normally (i.e orally) what would generally (i.e for most people) work better for pain control between 30mg MS Contin 3 times per day and 20mg Opana ER 2 times per day?
I'm a bit confused because of how low the oral bioavailability of Opana is (oral is barely 10% ). So taking a 20mg Opana ER would ultimately result in ~2mg being the proportion of a it that enters the circulation into the body and is thus able to have an active effect. At such a low bioavailability, wouldn't the MS Contin be better or is Opana/Oxymorphone really THAT strong that it would still be a better option?
The official conversion charts say a 90mg total MS Contin dose per day is equal to 15mg Opana ER twice per day but that doesn't seem to make any sense considering how radically awful the Opana bioavailability is.
I understand that Opana/Oxymorphone is insanely potent at 100% BA (i.e if used intravenously) but if that route isn't even an option (as far as I know Opana ER can't even be prepared for proper IV use due to abuse proofing - correct me if I'm wrong though) it just seems that MS Contin would be the better option.
If you guys had the option to choose between 3 x 30mg MS Contin per day and 2 x 20mg Opana ER per day, what would you select? MS Contin has poor oral BA too but even so, it's higher than 10%.
Also, on a side note... is it actually possible to prepare an Opana ER for IV use with a micron filter? It's my understanding that there is some sort of molecular bond or something in regards to the oxymorphone and time-release mechanism so wouldn't it basically be pointless to use a micron filter? Does anyone know if it's true that there's still some sort of generic Opana ER around than can actually be safely/easily prepared for IV?
Anyways, the main point here is legitimate pain control and the IV stuff is just out of curiosity. If 20mg Opana ER twice per day wouldn't generally cut it compared with 30mg MS Contin three times per day then what dose of Opana ER would cut it?
Last edited: