Limpet_Chicken
Bluelighter
- Joined
- Oct 13, 2005
- Messages
- 6,323
As this one really could go in many, many subfora, it was really a case of pick one and stick it there.
How potent are the dissociative type effects, compared to the likes of say, diphenidine, methoxphenidine when administered at a solid dose? because its looking likely I'll get the chance to try it, and a few analogs. I LOVED the other diarylethanamine NMDA antagonists mentioned (never tried ephenidine), although depending on the yield, I'll probably be constrained to either go for a small amount of one, and three others, or a good quality amount of one and two analogs (aimed at simple amine N-sulbstituents, isopropyl in particular, as so I've been told, 'isophenidine' has the lowest Ki for NMDARs of the lot, for simple such analogs, although I don't know if cyclopropyl was tested, or other cycloalkyl derivatives)
A mix of a DA-ergic stimulant, a dissociative and a mild opioid to smooth out any rough patches.
Thats one nice fucking three-in-one for a dissociative lover. Although I'm not confident I'd feel the opioidergic agonism through the morphine and oxy that I need to take courtesy of one fucked up everything but arse ring, dick and nackers on one side below the waist. At least if I want to be mobile enough to ever see it take shape, to be able to put together the equipment, and to be able to go and fetch the finished product from one place and bring it to another to ingest some, as I was badly injured as a kid. I'd love something I can use when the nerve pain gets beyond tolerance point and I'm close to breaking, because the opioids don't touch neuropathic pain (I fell on glass as a kid, driving a big upraised spike straight through my patellar tendon, into the joint, had to pull it out as best possible, snap off a foot or so of glass spike and walk home miles with the rest still in the joint, when I was maybe 9-11-12 or so at the oldest. Then in recovery, had it stamped on. Began many years of opioid pain management, which keeps the edges of the joint pain away, keeps the wolves from the door so to speak. But after further surgery, ended up with iatrogenic nerve damage.
Its no fun, and the only way that portion of the pain, as is well known, responds to opioids is a thorough knock-out dose of a potent opioid, sufficient to do just that-render me unconscious, along with the likes of chlormethiazole helping to sedate me, or chlormethiazole/nitrazepam. Just to avoid being there, when it gets past breaking point and cannot be tolerated. When everything below the waist down one side starts to burn like the fire rushing shrieking from the mouth of an oxyhydrogen fueled cutting torch, something has to be done. Its not scripted here that I know of, but, I am not without resources and the wherewithall to use them. I am looking into and my doc is supporting my getting off-label dispensation to get on memantine,something critical for quality of life anyway.
But I'd love to hear firsthand accounts of lefetamine use, since it has that three in one package deal so to speak, that seems like low doses would be perfect for some lab work, to give me some drive, some creativity and help dull the screaming, howling fury that is my knee, hips and other bits I didn't even know I had before they too started howling too. It's pushing it, now, for me to complete a project if it involves a day of work, and its really interfering with my work too. And that I cannot have.
How potent are the dissociative type effects, compared to the likes of say, diphenidine, methoxphenidine when administered at a solid dose? because its looking likely I'll get the chance to try it, and a few analogs. I LOVED the other diarylethanamine NMDA antagonists mentioned (never tried ephenidine), although depending on the yield, I'll probably be constrained to either go for a small amount of one, and three others, or a good quality amount of one and two analogs (aimed at simple amine N-sulbstituents, isopropyl in particular, as so I've been told, 'isophenidine' has the lowest Ki for NMDARs of the lot, for simple such analogs, although I don't know if cyclopropyl was tested, or other cycloalkyl derivatives)
A mix of a DA-ergic stimulant, a dissociative and a mild opioid to smooth out any rough patches.
Thats one nice fucking three-in-one for a dissociative lover. Although I'm not confident I'd feel the opioidergic agonism through the morphine and oxy that I need to take courtesy of one fucked up everything but arse ring, dick and nackers on one side below the waist. At least if I want to be mobile enough to ever see it take shape, to be able to put together the equipment, and to be able to go and fetch the finished product from one place and bring it to another to ingest some, as I was badly injured as a kid. I'd love something I can use when the nerve pain gets beyond tolerance point and I'm close to breaking, because the opioids don't touch neuropathic pain (I fell on glass as a kid, driving a big upraised spike straight through my patellar tendon, into the joint, had to pull it out as best possible, snap off a foot or so of glass spike and walk home miles with the rest still in the joint, when I was maybe 9-11-12 or so at the oldest. Then in recovery, had it stamped on. Began many years of opioid pain management, which keeps the edges of the joint pain away, keeps the wolves from the door so to speak. But after further surgery, ended up with iatrogenic nerve damage.
Its no fun, and the only way that portion of the pain, as is well known, responds to opioids is a thorough knock-out dose of a potent opioid, sufficient to do just that-render me unconscious, along with the likes of chlormethiazole helping to sedate me, or chlormethiazole/nitrazepam. Just to avoid being there, when it gets past breaking point and cannot be tolerated. When everything below the waist down one side starts to burn like the fire rushing shrieking from the mouth of an oxyhydrogen fueled cutting torch, something has to be done. Its not scripted here that I know of, but, I am not without resources and the wherewithall to use them. I am looking into and my doc is supporting my getting off-label dispensation to get on memantine,something critical for quality of life anyway.
But I'd love to hear firsthand accounts of lefetamine use, since it has that three in one package deal so to speak, that seems like low doses would be perfect for some lab work, to give me some drive, some creativity and help dull the screaming, howling fury that is my knee, hips and other bits I didn't even know I had before they too started howling too. It's pushing it, now, for me to complete a project if it involves a day of work, and its really interfering with my work too. And that I cannot have.