Everyone is different, some people have regained the magic whereas others haven't... It's an individual thing.
I used MDMA a lot of the time in combination with meth (this combo is a surefire way to fry your 5HT system and loose the magic, but it makes for a fucking awesome time, but there is a price) for 3 months every weekend straight. Eventually, MDMA stopped working for me and it would still fuck me up in a distinct way, but without the euphoria and emathy and the warmth that radiates from your body along with tactile sensation, music enhancement, enhanced colours etc... It's just a completely munted out feeling and not in a good way, you are just fucked up and not really enjoying it. So, I took a break and switched over to d-amphetamine with occasional methamp to try assist with the subsequent MDMA induced depression that followed the abuse and I now have an even higher tolerance to amps. Anyway, I waited 15 months after my last roll (end of 2012) and got ahold of a 160mg dutch press (which I had thought to be MDEA, but realised I was actually just loss of magic)... I tell you what, I was fucked up hard and munted, however it was nothing like MDMA used to be, no rolling feeling, just a subtle climb to the peak, floored the shit out of me and got me mega munted, but euphporia was very, very minimal and was more like being stoned with a clear head (after the peak) when it felt like a super clean speed high... Colours were slightly enhanced for a little bit. This was at a festival, with close friends who were rolling as well as a sexy chick I had met who was also rolling so set and setting can be ruled out. My next shot at it was 120mg of tested MDMA cystal, with the distinct safrole like smell, was brown rock and had that same old, soapy type taste to it... Again exact same thing, only I rolled (if that's what you could even call it) for about 40 minutes where I was again, distinctly fucked up, but with no euphoria... This was a week ago exactly as I type, infact I was at the peak at exactly this time 7 days ago ironically lol... I was at home with my girlfriend and it was far from a loved up experience. I plugged 120mg in her and I took it orally... Both the exact same thing (she also has a amphetamine tolerance and used to abuse MDMA like I did). Long story short, we were both very, very, very dissapointed in that the love drug that MDMA is and used to be caused us to feel fucked up, in a very bad way, we felt really emotionally flat especially when the comedown hit and yeah just a total fucking waste. Not only that, but I have been experiencing that shitty feeling reminiscent of my previous MDMA induced depression, just wierd moods, generally depressed on and off, moreso depressed than not, anxiety isn't much of a problem, but I certainly have been affected by it although nowhere near what it was the first time around. I think it can also be attributed to the fact that I am extremely disappoint in the experience in that we had such high hopes ot have a loved up roll but we ended up feeling shit and had a shit night. It failed us badly and instead of bringing us closer it did nothing and probably made it worse (her libido has been a bit flat since and she says she is feeling a little emotionally flat and drained) and I have been feeling shit.
I probably will not try MDMA again... However, if I ever have the chance to get my hands on some MDA you can take my word that I will snatch that shit up faster than a rabbit gets fucked. Almost everyone who has lost the magic with MDMA says that they have a full-blown roll on MDA. I believe as do others that it is not cross-tolerant or very minimally cross tolerant with MDMA (many people report back to back rolling on MDMA then MDA) and is far more intense. I have a feeling it is due to the fact that MDA is a direct agonist of the 5HT2B receptors and has a stronger affinity for the dopamine transporters than MDMA does, hence why it is more neurotoxic. Either way, MDMA won't work for me, but I would give one more time just too truly roll again. Another option is St Johns Wort which has supposedly been able to restore the magic for some people.
With that saying, I also have an amphetamine tolerance and IMO (there are others that agree, also posts online that agree with this theory) that if one has a NA/DA (adrenaline/dopamine tolerance) AKA tolerance to clasical stimulants I'm talking in my case and many others meth and regular amp that it will cause a diminished roll and you may not get any euphoria. A lot of people think it is all serotonin that does the work hence why an SSRI blocks it completely, but IMO dopamine and noradrenaline play just as an important part in the MDMA experience... If you have a tolerance to either of the 3 monoamines it will alter the effects of MDMA OR if you throw something in the mix like say meth, the ratio that MDMA releases the 3 monoamines willl be off and your experience will be different (more dopamine, by adding meth, produces a much speedier and adds to the euphoria, however like I said it will burn your out quicker and is proven to be more neurotoxic than either alone)... In saying that 3 of the best nights of my life was on a combo on MDMA and methamp but at the price of loosing the magic a lot quicker.