Buprenorphine is a mixed agonist/antagonist with uniqure properties that make it difficult to chart it's effects. In lower dosages, it seems to stimulate the Mu Opioid receptor at a much greater proportion relative to other Opioid I receptors. Buprenorphine (Buprenex) is a drug used in the clinical setting for pain management and the dosage units come in the form of 0.3mg intravenous if my memory serves me. This is just food for thought.
I typically never advise anyone t go above 8mg in any setting. I know there are so many conflicting experiences here, but I feel and also based upon personal research believe that anything above 8mg is going to increase physical dependence with a rapidly diminishing Mu receptor effect as the dosage is raised. In short, it's not linear. Yes, we are junkies and we're probably gonna take more and more until we're almost dead, but the smart move would be to induct using the microdosing method and get up to 8mg as quickly as possible.
200mg-400mg definitely isn't the worst I've ever worked on case-wise, but it's definitely gonna give you a nice rattle upon cessation, so being prepared is great, as you're trying to be. I encourage you very much to do your research on microdose induction as well as high-dose vs. low-dose benefits and make an informed decision.
If you have any questions or just wanna chat, hit me the fuck up dude.
