dopamimetic
Bluelighter
- Joined
- Mar 21, 2013
- Messages
- 2,070
Might it be possible to carefully titrate a combination of these two, to avoid serotonin depletion in attempt to recreate the 4,4'-dimethylaminorex experience?
Does serotonin syndrome come with a warning so you could snort an antagonist of choice or would it hit too fast? I've asked for reports about suspected serotonin toxicity in BDD, sorry for kinda cross posting.
As it is possible to safely titrate even stimulants on irreversible MAOIs, where the danger lies in hypertensive crisis which to me sounds equally bad if not even worse than serotonin syndrome, I wonder why nobody attempted this yet.
I wouldn't consider such a combo if I hadn't so glowing experiences with 4,4'-dmar (hell, even with some remaining venlafaxine in my system) which later turned out to be a SNDRA+MAOA-I.
Too I did extensively combine venlafaxine + DXM (pretty nice) as well as moclobemide + d-amphetamine (not recommended, 2mg required an acute administeration of clonidine and had no recreational effects whatsoever) and have been on SNRI for half my life which probably fucked my serotonin system and both originates my problems as well as makes me consider and maybe tolerate such extreme measures.
Of course it'd be better to do this first in a clinical setting but guess I'm out of luck here. Other possibility would be a mild SSRI + harmaline but guess this will primarily hit the autoreceptors.
In the end tobacco smoke contains afaik at least one MAOI and nobody gets serotonin syndrome from smoking on XTC. I talk about ridiculously low amounts, not unlike ultra low dose naltrexone! Just enough for a little boost. I urgently need something against my crippling social anxiety and low self esteem. Opioids, stims, booze, gabapentinoids, benzos failed, dissos are unpredictable and socially awkward from time to time and mess with memory.
Finally another possibility would be just harmaline as I have read that high doses of it are psychoactive on its own, just my trial of moclobemide 600mg/d made me loose hope in reversible MAOA-I alone. Maybe a threshold dose of tranylcypromine but I don't see myself maintaining a rigid diet, even right now I need to watch out for not to drift into malnourishment. And bleeding out of your eyeballs doesn't exactly sound like fun.
I remember once having very mild signs of serotonin syndrome from DXM + releaser (sweating, headache, possibly temperature) which wasn't pretty but faded away by itself. As I would do it while resting in a cooled room I guess hypertensive crisis might be worse? Would have a benzo handy for intranasal administration, unfortunately no serotonin antagonist.
Any thoughts?
Does serotonin syndrome come with a warning so you could snort an antagonist of choice or would it hit too fast? I've asked for reports about suspected serotonin toxicity in BDD, sorry for kinda cross posting.
As it is possible to safely titrate even stimulants on irreversible MAOIs, where the danger lies in hypertensive crisis which to me sounds equally bad if not even worse than serotonin syndrome, I wonder why nobody attempted this yet.
I wouldn't consider such a combo if I hadn't so glowing experiences with 4,4'-dmar (hell, even with some remaining venlafaxine in my system) which later turned out to be a SNDRA+MAOA-I.
Too I did extensively combine venlafaxine + DXM (pretty nice) as well as moclobemide + d-amphetamine (not recommended, 2mg required an acute administeration of clonidine and had no recreational effects whatsoever) and have been on SNRI for half my life which probably fucked my serotonin system and both originates my problems as well as makes me consider and maybe tolerate such extreme measures.
Of course it'd be better to do this first in a clinical setting but guess I'm out of luck here. Other possibility would be a mild SSRI + harmaline but guess this will primarily hit the autoreceptors.
In the end tobacco smoke contains afaik at least one MAOI and nobody gets serotonin syndrome from smoking on XTC. I talk about ridiculously low amounts, not unlike ultra low dose naltrexone! Just enough for a little boost. I urgently need something against my crippling social anxiety and low self esteem. Opioids, stims, booze, gabapentinoids, benzos failed, dissos are unpredictable and socially awkward from time to time and mess with memory.
Finally another possibility would be just harmaline as I have read that high doses of it are psychoactive on its own, just my trial of moclobemide 600mg/d made me loose hope in reversible MAOA-I alone. Maybe a threshold dose of tranylcypromine but I don't see myself maintaining a rigid diet, even right now I need to watch out for not to drift into malnourishment. And bleeding out of your eyeballs doesn't exactly sound like fun.
I remember once having very mild signs of serotonin syndrome from DXM + releaser (sweating, headache, possibly temperature) which wasn't pretty but faded away by itself. As I would do it while resting in a cooled room I guess hypertensive crisis might be worse? Would have a benzo handy for intranasal administration, unfortunately no serotonin antagonist.
Any thoughts?