you should really look into actual research on effective dosage for CBD. it varies depending intention(i.e. pain, anxiety), but it's efficacy is said to be around 10-25/mg per body weight. I think that number might come from dosages for effective epilepsy treatment, but there is research on what they call the "bell shaped curved" of the effectiveness of CBD. Most in the circle I get my info, who are currently working in the industry at various levels, say 4-500mg per dose for the average person. So maybe 2-300 for a smaller female, and 6-800mg for a larger male.
But that is also assuming that the male and female body process the drug the same. A ton of research recently has come out as to why certain treatments have drastically different outcomes for male vs female. A common example is how females are generally more sensitive to alcohol, due to a higher fat to water content, and less alcohol dehydrogenase, the enzyme that breaks down alcohol as begins to process of removing it from the body. Similarly, some Asians also have lower levels of this enzyme, which is why the stereotype of an Asian girl not being able to handle her alcohol is often true. Genetically, they are not evolved to handle it well/ be more sensitive to it- at least by comparison.
Among the vast assumptions made in CBD treatments(not saying there isn't legit ones, just lots of false info), Route of administration(ROA) is another thing that I rarely hear considered when dosing, despite it playing a rather big effect in the process. Vaping, as I understand, bypasses the first pass metabolism(stomach acids, liver, etc), but the drug still interacts with enzymes in the lung(p450?). I also know of a company that nanoencapsulates the CBD so that it can be dissolved under the tounge, bypassing first pass metabolism this way as well. I think something similar can be achieve with something like tincture/alcohol, as I do not think CBD is water soluble, which would also rule out snorting and(most unfortunately)boofing as effective methods. Unless of course there was similar means to bypass the same problem as holding cbd crystal under your tongue.
