Glycine is one of the body's main inhibitory neurotransmitters and works synergistically with GABA (our main inhibitory neurotransmitter). Glycine binds to GABAA receptors - the target of most of the common GABA-ergic drugs. Together, GABA and glycine are reponsible for REM atonia/sleep paralysis.
This study suggests a possible interaction between benzodiazepines and glycine receptors that may contribute to their anxiolytic, anticonvulsant and muscle-relaxing properties.
http://www.ncbi.nlm.nih.gov/pubmed/4152296
Studies show that oral glycine crosses the blood-brain barrier, shortens sleep latency, improves sleep quality and reduces daytime fatigue when taken before bedtime.
So is glycine at all psychoactive? Does it have any muscle relaxant properties? Would it potentiate the effects of Valium or other GABAergic drugs?
Thanks.
This study suggests a possible interaction between benzodiazepines and glycine receptors that may contribute to their anxiolytic, anticonvulsant and muscle-relaxing properties.
http://www.ncbi.nlm.nih.gov/pubmed/4152296
Studies show that oral glycine crosses the blood-brain barrier, shortens sleep latency, improves sleep quality and reduces daytime fatigue when taken before bedtime.
So is glycine at all psychoactive? Does it have any muscle relaxant properties? Would it potentiate the effects of Valium or other GABAergic drugs?
Thanks.