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Opioids Experienced IV users... help... shot up for the 1st time

I can attest to the "Histamine Headache" from a massive histamine release. It was awhile back but terrifyingly painful and incapacitating . It begins with the familiar histamine hives or urticaria followed by a red flushed face that feels like an overinflated balloon and then the headache that comes on in waves and makes one hold very still, trying to keep your pulse and BP as low as possible until it passes after about 15 mins, the longest 15 mins of my life. I'll stop here as I already explained it in post #7

It's the reason I'd recommend going slow with IV'ing until about a third is in and you can judge the amount of histamine release. I've stopped after 2/3 was in and proceeded with the remainder at a very slow pace when I knew the H1 release was turning me into a tomato. Also safer than fast shots when gauging potency of H that could possibly contain Hot Spots of H or Fent. Antihistamines can also help to a certain extent with H1 release.
 
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