If I take MDMA and the next week 3MMC/coke, will I have some 3MMC tolerance built up? According to psychonaut it takes 1-2 week to get to baseline so I wonder if it accumulates from all stimulants or what is the interaction among those?
MDMA should get to the baseline after 2.5 months but I guess it does not affect other stims for so long, or?
What are you talking about? 2.5 months? Don't believe the bullshit that you have to wait 3 months between dropping MDMA because that's exactly what it is, bullshit!
I'm not saying go out there and drop a pill every single week, although I did that for multiple years.
However, there is no science to support the baseless statements of "you have to wait 3 months between MDMA doses or you're going to damage your brain"
In fact, the evidence shows there's no difference in serotonin transport between prior users of MDMA and people that never have.
"There was no significant difference of serotonin transporter availability among former MDMA users and the drug-naive and polydrug comparison subjects."
OBJECTIVE: Recent functional imaging studies have reported evidence of alterations in the serotonergic system induced by 3,4-methylenedioxymethamphetamine (MDMA), or “Ecstasy.” However, these studies have often been limited by small sample size, lack of tracer selectivity, unreliable assessment...
ajp.psychiatryonline.org
Alexander Shulgin reported that tolerance to MDMA was abolished after as little as 1 week abstinence, after multiple doses on consecutive days to test tachyphilaxis and cross-tolerance to MDA (It's not cross tolerant with MDA by the way).
I can personally attest that MDMA tolerance completely disappears within a week.
There is zero cross-tolerance between MDMA and cocaine.
I am not aware of cross-tolerance between MDMA and 3-MMC, although I cannot definitively say no.