Limpet_Chicken
Bluelighter
- Joined
- Oct 13, 2005
- Messages
- 6,323
Well then. Been doing a bit of reading, and getting some 'black tar' heroin, which in this particular case, is NOT the standard BTH (black tar heroin), that goes around the US, but rather, an alkaloidal extract of opium which has been acylated with propionyl chloride, rather than acetylated as usually happens. Not a commercial product, but one of those things one occasionally, if lucky, runs into when somebody gets enterprising
Lets not go into synthesis discussion at all, that isn't nescessary information anyway to me, I already understand the chem that will have gone into it, it isn't exactly advanced or complex to begin with.
What I want to know is, acetylcodeine is known to be dangerous when IV'ed. I certain't will NOT be using this intravenously, plugged or possibly nasally, although given my oxycodone tolerance (need 2 OC80s a day, min. thanks to my screwed up joints and bursitis).
HOW is this toxicity exerted? I have read two different theories-one, that it may be a convulsant, somebody here in a thread found via TFSE stated that acetylcodeine is 2-3x as potent of a convulsant when used intravenously as diacetylmorphine..that seems an acceptable risk for non-parenteral use, if treated with care.
The other theory, seems to revolve around potential for massive histamine release, which is also known to be the mode by which regular, un-acylated codeine is toxic, resulting in pulmonary oedema when taken intravenously. Which, as stated, will not be happening..ick..gross. I can't even imagine shooting black tar itself, although to the best of my knowledge, BTH is a US/mexican thing really and doesn't exist in the UK.
Lets not go into how to make such a product, such information is available if anybody wishes to put the effort into seeking it out, and I do not need to do so, nor do I want this thread shut down because someone else starts posting synth info.
Is it known if propionylcodeine shares in the toxicity of acetylcodeine? I am going to assume that it does indeed do so unless presented with reliable information to the contrary. In this product I'll be trying out, some propionylcodeine will undoubtedly be present, but given the ratio of codeine:morphine in most opium I would imagine that there probably isn't going to be a great deal, and that given the great potency of dipropionylmorphine, an active dose of the latter should be able to be dosed enterally without too much risk? of course, antihistamines would be preloaded anyway, as I do with most opioids regardless, to prevent excessive histaminergic effects.
Can anybody provide solid tox. data on propionylcodeine? also solubility data in various solvents would be most appreciated, I'd like to wash out this impurity.
Lets not go into synthesis discussion at all, that isn't nescessary information anyway to me, I already understand the chem that will have gone into it, it isn't exactly advanced or complex to begin with.
What I want to know is, acetylcodeine is known to be dangerous when IV'ed. I certain't will NOT be using this intravenously, plugged or possibly nasally, although given my oxycodone tolerance (need 2 OC80s a day, min. thanks to my screwed up joints and bursitis).
HOW is this toxicity exerted? I have read two different theories-one, that it may be a convulsant, somebody here in a thread found via TFSE stated that acetylcodeine is 2-3x as potent of a convulsant when used intravenously as diacetylmorphine..that seems an acceptable risk for non-parenteral use, if treated with care.
The other theory, seems to revolve around potential for massive histamine release, which is also known to be the mode by which regular, un-acylated codeine is toxic, resulting in pulmonary oedema when taken intravenously. Which, as stated, will not be happening..ick..gross. I can't even imagine shooting black tar itself, although to the best of my knowledge, BTH is a US/mexican thing really and doesn't exist in the UK.
Lets not go into how to make such a product, such information is available if anybody wishes to put the effort into seeking it out, and I do not need to do so, nor do I want this thread shut down because someone else starts posting synth info.
Is it known if propionylcodeine shares in the toxicity of acetylcodeine? I am going to assume that it does indeed do so unless presented with reliable information to the contrary. In this product I'll be trying out, some propionylcodeine will undoubtedly be present, but given the ratio of codeine:morphine in most opium I would imagine that there probably isn't going to be a great deal, and that given the great potency of dipropionylmorphine, an active dose of the latter should be able to be dosed enterally without too much risk? of course, antihistamines would be preloaded anyway, as I do with most opioids regardless, to prevent excessive histaminergic effects.
Can anybody provide solid tox. data on propionylcodeine? also solubility data in various solvents would be most appreciated, I'd like to wash out this impurity.