Start by drawing as much from the cotton as you can (0.5ml total water should be applied at first with 1cc syringe use) , attaching a .22 micron filter, pushing out into a receptacle. Then immediately after rinse your cottons and leftover pill powder with another 0.5ml water and repeat the filter process, emptying into same receptacle as first wash solution. I read in a study I found on here awhile back that this was actually a safer way to inject pills as no particulate is picked up and you get a full reliable dose in one go.