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Cyclobenzaprine as a trip killer: 5-HT2 Antagonism?

theprinceoflife

Greenlighter
Joined
Feb 18, 2023
Messages
14
Would cyclobenzaprine (a muscle relaxant) work to end a psychedelic trip? It antagonizes the same same receptor that most tryptamines/psychedelics would be working on.
 
Yeah, it should work for that. People use trazodone for a similar reason because it lacks some of the antidopaminergic effects of antipsychotics while blocking 5HT2A.

Apparently cyclobenzaprine doesn't play nice with MAOIs, so no using it with ayahuasca or the 2cT compounds.
 
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