Clomiphene + Anastrozole + Dextroamphetamine + GHB + Metformin = Superman Regimen?

[InfectedWithDrugs]

My stats, info, diet, workout:
I'm a 29 year old male, 6'0ft high, 191lbs, about 18% body fat, body type - a lot like Ryan Reynolds (except that he is ripped and I am far from it). My goal is first to get really lean (10% BF) within 3-4 months, and then slowly and carefully bulk for 6 months, and then cut again. Ultimately I want to be at 10% BF @ 200lbs one day.

I spend about 40-50 minutes in the gym lifting weights intensely (Push/Pull/Legs 3-day split), followed by 45-60 minutes cardio either immediately after lifting or some 6-9 hours later. On some days, I do 30-minute cardio on empty stomach, BUT I am not sure that you can call it "empty stomach" because I am pre-diabetic and my morning fasting glucose level is between 110-120, almost levels of Diabetes Type II. I don't do HIIT because its too hard for me in this state (read later about my withdrawals).

My diet is superb IMO - 1.2g of protein per lean body mass (about 200g of protein) + 0.4g of fat per lean body mass + up to 100g of unprocessed carbs (although too many come from fruits...) + 4g of fish oil + multi-vitamin + magnesium oxide 500mg + 4000 UI Vitamin D3. Based on many calculations I performed, my BMR is at about 1900-2000 calories and TDEE is at about 2400 calories because of my very sedentary life style, but the 500 calories on top of BMR for TDEE come from daily lifting and cardio. I eat about 1800 calories per day total. I record every single caloric intake with SparkPeople Android App and weigh every single serving to be very precise.





A few months back I was diagnosed with low T and high E2 (Total T less than 250, Ultra-sensitive E2 was at 45), and after being put on clomiphene citrate 50mg ED+ anastrozole 0.5mg ED, my Total T rose to 1200 and Free T rose to 26, while Ultra-sensitive E2 levels fell to 29. It changed my life around - I felt incredible! In 2 months I went from 217lbs @ 25-30% BF to 191lbs @ 18% BF, but progress slowed down to where I lose 1lbs per week now. Before this I was mis-diagnosed as having Bipolar Disorder Type II due to mood swings, which also happens to be a a major symptom of low T (hypogonadism). Then the fun sort of stopped because I decided to come off all my bipolar and other medications at once cold turkey - gabapentin, tiagabine, buprenorphine patches, baclofen, hydroxyzine, trazadone, dextroamphetamine, lamotrigine, and even omeprazole. I didn't need them, but weeks later I am experiencing withdrawal symptoms similar to those from Xanax, just not as bad and its mostly withdrawal from GABA A drugs (gabapentin, tiagabine). The main symptoms are fatigue, anxiety, insomnia, sweaty palms. Every time I try to take something for anxiety or insomnia, like trazadone and hydroxyzine, my water weight starts climbing until those drugs are completely out of my system. I think all them doozies lower metabolic rate, so I stay away from them.

I am also prescribed Xyrem, which is GHB (GABA B agonist) and its a double-edged sword for me. It puts me asleep, but I wake up with an unpleasant dopamine rush and increased anxiety. If I do not use it, I get maybe 1hr of sleep per week and just cannot be hitting the gym in that condition. Not only that, but GHB raises prolactin levels, which reduces testosterone. I think it also kills sperm count because if I take it, my semen becomes transparent and if I do not take it, it turns white... Weird! My other alternative is to keep taking dextroamphetamine (10mg BID) which ALSO decreases testosterone and many say its CATABOLIC... Finally, for my pre-diabetic condition I could also be taking metformin, which ALSO decreases testosterone...

Assume I want to speed up my fat loss process, which drugs should I stick to - dextroamphetamine, GHB, metformin or all 3? All 3 reduce testosterone levels, but I am curious whether it would make a difference when Total is at 1200 and Free T at 26, both of which are ABOVE the healthy range (when not using GHB, dextroamphetamine, and/or metformin). I do not want to lose much muscle, although I know I will one way or another. I only got 15lbs to lose before I achieve my body fat goal.

What would you advice?
​

 

[CFC]

Hi mate, long post and lots of question there. Given your background (which you haven't really explained), you should absolutely discuss anything you do choose to change with your GP or specialist. Whatever is wrong with you seems to be pretty severe given all you've been prescribed.

My first advice would be to give yourself at least 3+ months to properly withdraw from that pharmacy drugs you were on before worrying about weight loss! Seriously, I'm not surprised your test levels were screwed and you became fat.

Second, now your test levels are up, drop the clomid but maintain the anastrazole. Your relatively high 'natural' E2 suggests control of aromatase is the main area to focus on. Your T levels will probably fall a bit, but see how far first.

Third, you don't explain why you have insomnia, but if you need the xyrem to sleep, that should be your priority. The effect on T is of tertiary concern given the importance of stage 3/4 sleep. You should discuss the rebound with your GP (eg - take less, take other meds to lower dopamine, try other sleeping meds like alpha-2 adrenergic agonists).

Fourth, you also don't explain why you're on amps, but that's surely not helping your insomnia. Absolutely don't take them if you don't need them.

Fifth, don't take the metformin until you're fully over the withdrawal from the other meds. Has your fasted BG been improving since you lost some of the weight? Many people find pre-diabetes recedes once they become healthy and fit again.

Sixth, and most importantly, 1lb of weight loss per week is excellent! You have to understand that as you become leaner, your weight loss will slow and slow until it stops. You cannot sustain rapid weightloss indefinitely. But I wouldn't worry about it until you're only losing, say 1lb per 3-4 weeks. And when that happens, that's when you have to start being clever with how you eat and train, like introducing 1-2 days where you eat far more food or carbs to reignite your metabolism.

 

[InfectedWithDrugs]

Thank you for reading my thread and huge thanks for your recommendation. I numbered replies accordingly:

1 - Yeah, I thought about it, but I am unemployed at the moment and although I actively seek work and volunteer at a local hospital, I feel like NOT hitting the gym and self-improving my body is a waste. Sure, I can't do it at 100% like I could if I was not in WD, but I already went from 217lbs to 191lbs. Another issue is that my appetite is really bad right now. Normally I love to eat, but these days 1500 calories per day seems too much - again, due to withdrawal and nausea. I force myself to eat 1800-1850 calories, otherwise extreme caloric deficit will cause muscle loss (or at least more of it), which I do not want since I barely have muscle on me. When I reach them 10% BF - I will be at about 175lbs and for someone who's 6'0ft tall, that is SCRAWNY. Normally, I would bulk at this stage, but I am already 29 and people tell me I look 20 - baby face, which has now been drastically improved after losing some 23lbs. Once I get ripped - I will get my defined chiseled face I always wanted

2 - I had my T tested when I was not on any drugs and it was just as low - Total T around 350-400, which is within range, but for men in their 60's. As a kid I got Mumps and Mumps can permanently mess up a man's testosterone levels + I was kicked in the nuts several times in my life. Before any of the mentioned drugs I kept getting mood swings, hot flashes, depressions, etc. That is WHY I was mis-diagnosed with BPII, even though I begged my family doctor and P.A. to prescribe me low-dose steroid to make sure my T isn't the cause of my problems. Those doctors ripped 10 years out of my life by putting me on a ton of worthless meds for a condition I did not have. So, I DO need clomiphene citrate and anastrozole at these exact doses if I want to keep feeling good. Those 2 drugs are a MUST. I also had major back surgeries, which left me in pain and made me opiate-dependent. Testosterone plays a HUGE role in pain threshold, which is how I managed to quit opiate use within 2 months with 0 withdrawals and my pain used to be at 7-8/10, now at 2-3/10. My Total T was at 125 when I was taking buprenorphine (without Clomid). I also agree that aromatization due to high body fat % plays a major role. When I was a teenager, I developed a mild case of gynocomastia, which was later surgically removed (and surgery was freaking FREE!). That again points of high levels of aromatization. Once I get down to 10% BF or so, I will either stop taking anastrozole or reduce it and/or possible reduce Clomid, as long as my Total T is at 1000 or above, Free T at 22 or above and E2 below 30, but it depends on the healthy range the laboratory uses.

3 & 4 - My insomnia began when I stopped taking gabapentin (GABA A analogue) and tiagabine (GABA re-uptake inhibitor), both of which increase GABA A in brain and body (and cause SEVERE weight gain!). I tapered for a week like the doctor told me, but once I stopped - sh*t hit the fan. About 3 years ago I had to come off 2mg of Xanax (took it for a year) and WD were so bad that doctor prescribed gabapentin and tiagabine for anxiety, which worked, BUT I think they prevented full benzo WD from taking place. Now it feels like a continuation... I was diagnosed with Narcolepsy which is why I was prescribed Xyrem and amphetamines. However, back then I was on Xanax, OxyContin, Lyrica, and some other drugs, so my new sleep specialist thinks I do NOT have Narcolepsy and that it was drug-induced. Yet another doctor says otherwise because none of the drugs I was taking can induce REM sleep within 10 minutes, which is how quickly I reach it. Normally it takes hours to reach REM sleep, but I get into it in 10 minutes. I RARELY take amphetamines - maybe 1-2x per week 10mg pure dextroamphetamine and I do it on fasting stomach cardio. I was doing research today and it appears amphetamines are BAD BAD BAD for people with elevated sugar. They further increase glucose levels and can sometimes even induce Diabetes Type II. Bottom line - NO MORE amphetamines for me. However, that means that 60 minute morning cardio will have to be spread across 2x 30 minute sessions because amphetamines pump me the hell up and I can run + lift more with them than without them.

5 - When I was 217lbs and on a ton of those drugs, my sugar level was actually lower - 110, but now its at 115-120... I barely eat any carbs, thinking of doing ketosis with sub-50g of carbs per day. Its also bad that the only carbs I like are high-glucose fruits, like pine-apple, mango, peaches, oranges, bananas, etc. I just know Metformin can greatly AID in fat loss. My AST blood test result is also bad (elevated liver enzyme) - healthy range is up to 42 and I am at 60...

6 - I am concerned that having pre-diabetic sugar levels will prevent me from reaching my goals and getting really fit... I am not impatient, but I am so sick of high BF% that I want to utilize all tools available to me to make it happen. However, when I was 19, I ended up losing a lot of muscle mass and little fat, but back then I did not even bother counting my calories, just ate very little. I was actually 160lbs at 18% BF. Super-scrawny. This time I doing it THE RIGHT WAY. Now I have the same BF%, but at 191lbs after I bulked up in college (muscle memory is a true thing!).

Another big problem is that I should be eating healthy meats, fish, and natural proteins, but I get about 60% of protein from such sources, the rest comes from whey protein because of nausea and bad appetite due to withdrawal. Finally, the re-carb days drive me NUTS because I weight myself daily and my weight goes up 3-5lbs for the next few days and it freaks me out, even though I know its only water-weight because its IMPOSSIBLE to gain 3lbs of fat in a day with a caloric deficit... I try to have 1 re-carb day per week.

 

[Intense]

All that^ lol (referring to CFC)


And additionally, sperm color has nothing to do with sperm count.

I have been blasting and cruising and am completely shut down, nuts are tiny but my loads are big and white. My FSH and LH are non existent.. Now if I jerk off 5 times a day my loads will be a little thinner. Everyone is different. Maybe up your celery intake lol.

 

[InfectedWithDrugs]

Forgot to mention that Xyrem/GHB is prescribed to be taken 2x per night, where each dose provides about 4 hours of sleep for a normal person, but due to my WD I get about 3 hour of sleep from each dose. If I take only ONE dose, then rebound effect is barely there, but I would only get 3 hours of sleep per night... Another problem is at night my body itches (benzo, gabapentin, tiagabine WD) and Xyrem/GHB alleviates it. The itch disappears in the morning, but often times I just can't take it at night and drink another dose of Xyrem/GHB, then wake up with tachycardia, anxiety, and dopamine rush of epic proportions. My appointment to sleep specialist is in 2 months, no sooner because he's so booked.

 

[CFC]

1 - Yeah, I thought about it, but I am unemployed at the moment and although I actively seek work and volunteer at a local hospital, I feel like NOT hitting the gym and self-improving my body is a waste. Sure, I can't do it at 100% like I could if I was not in WD, but I already went from 217lbs to 191lbs. Another issue is that my appetite is really bad right now. Normally I love to eat, but these days 1500 calories per day seems too much - again, due to withdrawal and nausea. I force myself to eat 1800-1850 calories, otherwise extreme caloric deficit will cause muscle loss (or at least more of it), which I do not want since I barely have muscle on me. When I reach them 10% BF - I will be at about 175lbs and for someone who's 6'0ft tall, that is SCRAWNY. Normally, I would bulk at this stage, but I am already 29 and people tell me I look 20 - baby face, which has now been drastically improved after losing some 23lbs. Once I get ripped - I will get my defined chiseled face I always wanted

Yeah sorry I don't mean stop training. Training will help tons. I just meant stop worrying prematurely. Eat as best you can for now, making sure you get fats and protein. You can worry about fine details after you're properly recovered.

2 - I had my T tested when I was not on any drugs and it was just as low - Total T around 350-400, which is within range, but for men in their 60's. As a kid I got Mumps and Mumps can permanently mess up a man's testosterone levels + I was kicked in the nuts several times in my life. Before any of the mentioned drugs I kept getting mood swings, hot flashes, depressions, etc. That is WHY I was mis-diagnosed with BPII, even though I begged my family doctor and P.A. to prescribe me low-dose steroid to make sure my T isn't the cause of my problems. Those doctors ripped 10 years out of my life by putting me on a ton of worthless meds for a condition I did not have. So, I DO need clomiphene citrate and anastrozole at these exact doses if I want to keep feeling good. Those 2 drugs are a MUST. I also had major back surgeries, which left me in pain and made me opiate-dependent. Testosterone plays a HUGE role in pain threshold, which is how I managed to quit opiate use within 2 months with 0 withdrawals and my pain used to be at 7-8/10, now at 2-3/10. My Total T was at 125 when I was taking buprenorphine (without Clomid). I also agree that aromatization due to high body fat % plays a major role. When I was a teenager, I developed a mild case of gynocomastia, which was later surgically removed (and surgery was freaking FREE!). That again points of high levels of aromatization. Once I get down to 10% BF or so, I will either stop taking anastrozole or reduce it and/or possible reduce Clomid, as long as my Total T is at 1000 or above, Free T at 22 or above and E2 below 30, but it depends on the healthy range the laboratory uses.

You misunderstand me mate, I'm not disagreeing that you have a T problem. But anastrazole is also raising your T levels by lowering your E levels --> in blocking conversion to E2, circulating test and DHT (and other neurostimulating metabolites) rise immediately, and by lowering E, T rises even further - it's a classic virtuous cycle. It's also by far the nicer of the two drugs on the body. So drop the clomid when you feel ready and just see how you go. You can always restart clomid later (or at half the dose) if you don't feel right. Ultimately if your T doesn't recover, you'd be better on TRT than clomid/anast.

3 & 4 - My insomnia began when I stopped taking gabapentin (GABA A analogue) and tiagabine (GABA re-uptake inhibitor), both of which increase GABA A in brain and body (and cause SEVERE weight gain!). I tapered for a week like the doctor told me, but once I stopped - sh*t hit the fan. About 3 years ago I had to come off 2mg of Xanax (took it for a year) and WD were so bad that doctor prescribed gabapentin and tiagabine for anxiety, which worked, BUT I think they prevented full benzo WD from taking place. Now it feels like a continuation... I was diagnosed with Narcolepsy which is why I was prescribed Xyrem and amphetamines. However, back then I was on Xanax, OxyContin, Lyrica, and some other drugs, so my new sleep specialist thinks I do NOT have Narcolepsy and that it was drug-induced. Yet another doctor says otherwise because none of the drugs I was taking can induce REM sleep within 10 minutes, which is how quickly I reach it. Normally it takes hours to reach REM sleep, but I get into it in 10 minutes. I RARELY take amphetamines - maybe 1-2x per week 10mg pure dextroamphetamine and I do it on fasting stomach cardio. I was doing research today and it appears amphetamines are BAD BAD BAD for people with elevated sugar. They further increase glucose levels and can sometimes even induce Diabetes Type II. Bottom line - NO MORE amphetamines for me. However, that means that 60 minute morning cardio will have to be spread across 2x 30 minute sessions because amphetamines pump me the hell up and I can run + lift more with them than without them.

Yes amphetamines can raise blood sugar further, though at low doses not much. But I agree, it's better if you can cope without. As for xyrem, can you titrate the doses down? If you can lower them enough for them to still work, that may help. Alternatively you should consider discussing (for example) clonidine with your GP or specialist, since not only does adrenergic blockade help you reach stage 3/4 sleep, it's also great for most typical WD symptoms like itching, jitteriness etc.

5 - When I was 217lbs and on a ton of those drugs, my sugar level was actually lower - 110, but now its at 115-120... I barely eat any carbs, thinking of doing ketosis with sub-50g of carbs per day. Its also bad that the only carbs I like are high-glucose fruits, like pine-apple, mango, peaches, oranges, bananas, etc. I just know Metformin can greatly AID in fat loss. My AST blood test result is also bad (elevated liver enzyme) - healthy range is up to 42 and I am at 60...

You need to resensitise your muscles (and liver) to insulin, which exercise and weightloss does very effectively over time. Plus a fatty liver always takes a while to fix, regardless. Since a lot of the damage stems from free-radical excess, a healthy diet (lots of veg/fruit, protein and good oils) and exercise can help break the vicious cycle. Metformin can too, it's just a question of do you want to add yet another drug to your system, or do you want to see if you can achieve it naturally first?

As for the fruits, they're really not that much of a problem as they're low GI - you're getting small amounts of sugar mixed with fibre and water. If you take them after mealtimes it can help lower GI further though. Do try to avoid whey if you can though, tends to elevate insulin quite significantly. Go with casein, and/or drink it only along with solid food.

6 - I am concerned that having pre-diabetic sugar levels will prevent me from reaching my goals and getting really fit... I am not impatient, but I am so sick of high BF% that I want to utilize all tools available to me to make it happen. However, when I was 19, I ended up losing a lot of muscle mass and little fat, but back then I did not even bother counting my calories, just ate very little. I was actually 160lbs at 18% BF. Super-scrawny. This time I doing it THE RIGHT WAY. Now I have the same BF%, but at 191lbs after I bulked up in college (muscle memory is a true thing!).

Another big problem is that I should be eating healthy meats, fish, and natural proteins, but I get about 60% of protein from such sources, the rest comes from whey protein because of nausea and bad appetite due to withdrawal. Finally, the re-carb days drive me NUTS because I weight myself daily and my weight goes up 3-5lbs for the next few days and it freaks me out, even though I know its only water-weight because its IMPOSSIBLE to gain 3lbs of fat in a day with a caloric deficit... I try to have 1 re-carb day per week.

Don't be. Give it some time. You're worrying about, and trying to pre-empt, something that hasn't actually happened. Your weightloss is going at an optimal rate. Have some faith in your body mate lol. It'll recover just fine if you give it a chance and some time Just keep up the motivation and stick to it relentlessly. And keep your ideal body in mind whenever you start to falter.

 

[CFC]

All that^ lol (referring to CFC)


And additionally, sperm color has nothing to do with sperm count.

I have been blasting and cruising and am completely shut down, nuts are tiny but my loads are big and white. My FSH and LH are non existent.. Now if I jerk off 5 times a day my loads will be a little thinner. Everyone is different. Maybe up your celery intake lol.

Yeah lol. Most guys assume their cum volume comes from the testes, rather than the prostate, seminal vesicles etc.

 

[InfectedWithDrugs]

Thank you for support.

I saw many people advising TRT with an AI instead of Clomid and AI. Why is that? TRT can mess up a guy's fertility and make balls smaller, while Clomid does the opposite.

I saw many reports about Clomid making men emotional and losing libido. I do not have those issues, although I used to have a higher sex drive when not on drugs. Since my body is in extreme state of anxiety, I can see how libido is not at its best in this condition...

BTW, nobody answered whether people with Type II Diabetes can even achieve low body fat percentage...

 

[InfectedWithDrugs]

Clonidine does not help in any way with any of the WD. I have it and it used to help with opiate WD big-time, but for post-acute benzo WD it only makes me tired, but not sleepy, and of course it causes weight gain (increases water retention). Here goes another night I wish I could spend without Xyrem, but my chest is itchy like hell and hydrocortisone, aloe, ibuprofen, and even lidocaine creams do absolutely zilch for this itch.

 

[InfectedWithDrugs]

Well I found out hydroxyzine at 100mg nearly puts me asleep, but it causes drastic water weight gain like gabapentin. I might stick to it for a week or so and see if I can avoid Xyrem, start sleeping on my own...

 

[CFC]

Thank you for support.

I saw many people advising TRT with an AI instead of Clomid and AI. Why is that? TRT can mess up a guy's fertility and make balls smaller, while Clomid does the opposite.

I saw many reports about Clomid making men emotional and losing libido. I do not have those issues, although I used to have a higher sex drive when not on drugs. Since my body is in extreme state of anxiety, I can see how libido is not at its best in this condition...

BTW, nobody answered whether people with Type II Diabetes can even achieve low body fat percentage...

The issue most have with long-term clomid use is its potential for genotoxicity (basically, causes DNA damage).

Yes, you can be lean and have type-2. There are Olympic athletes with it.

 

[Genetic Freak]

Regarding GHB use and waking up with tachycardia etc..
GHB is dose dependant stimulant/cns depressant..
At doses around 1.5g it acts on GHB receptors as a stimulant... Above about 3.5g it acts upon GABA-B receptors as cns depressant..
Once the 3.5g metabolises down to about 1.5g the user bounces up awake..
Unfortunate but not a lot you can do about it...

 

[InfectedWithDrugs]

The issue most have with long-term clomid use is its potential for genotoxicity (basically, causes DNA damage).

Yes, you can be lean and have type-2. There are Olympic athletes with it.

Damn it... There I thought I found a healthy solution to my problem. Clomid causes cancer... What other solution is there? HCG + steroids? Which steroids? I would only go for a steroid with a long half life - I don't need ups and downs in my T levels because then I get mood swings...

 

[xtcbiz]

The key thing you need to recognize here is that anything 'synthetic' you take, from the extremely powerful pharmaceutical drugs you are on to the artificial foods like diet soda or even beer will have a negative effect on your Test levels.

The optimum setup for your best test levels is a 100% whole food diet, solid deep sleep nightly, and daily consistent light to moderate intensity workouts. In real life this is very difficult to actually consistantly maintain, at least for myself.
I did a lot of testing on myself when i thought i had some low test problem, but basically the conclusion I came to is your Test levels can be dramatically different from one day to another. 10-20% difference easy, sometimes 50% in extreme cases.

Just work with what you have and avoid crashes throughout the day.

For example in the morning your test levels are the highest, and then your t/e ratio falls as the day goes by. It can be extremely low by say 8PM and your estrogen can be really high at night because all your test has aromatized into estrogen, but by next morning it should be back to normal.

Then lots of external things we consume can really effect your intra-day test levels. For example too much glucose at one time can crash your test levels, soda, alcohol, etc.

Having shitty sleep as a result of caffiene can result in bad next day test levels.

Walking 1 mile is as effective at lowering blood sugar as metrofrmin, at least that is what I have read.

I think for you, number one priority is to drop all drugs you are on, including Xyrem as soon as possible. Then do only clomid to fix your testosterone levels, if you can. Having good test levels should get you to sleep extremely well.

I think you should walk a lot plus clomid to keep your test levels up. Hopefully this can fix your blood sugar issues.
Clomid and arimidex combo is good too, but focus mainly on using clomid and not arimidex. Arimidex will fuck you up mentally much more then clomid.
Also Arimidex is very bad for bone density, don't mess around with Aromatase inhibitors if you don't have to. You can eat Calcium D glucurate pills or Brocolli/cabbage to flush estrogen out of your system (natural anti estrogen ).

You clearly need to get your high blood sugar fixed up, so I would use clomid to help you lose weight by doing lots of cardio. Way more then only 60 minutes per day. That's nothing. I know too much cardio will lower test, but with clomid on hand you don't have to worry about this as much. Clomid should keep your test levels up high even if you are over training.


Injecting test will most likely directly fix your metabolic problems much faster, (especially the elevated glucose issue) but then you will be stuck with the responsibilty of being on test forever.

 

[CFC]

Damn it... There I thought I found a healthy solution to my problem. Clomid causes cancer... What other solution is there? HCG + steroids? Which steroids? I would only go for a steroid with a long half life - I don't need ups and downs in my T levels because then I get mood swings...

As suggested before, you could try the AI by itself for a while. If that doesn't work, you could give a shot of triptorelin acetate a go. Then of course there's TRT and/or long-term low dose hCG as a last resort. Unfortunately there's no perfect/easy solution, however I'd wait until you're well recovered before embarking on any radical changes, and work with your endocrinologist if you can.

 

[InfectedWithDrugs]

The key thing you need to recognize here is that anything 'synthetic' you take, from the extremely powerful pharmaceutical drugs you are on to the artificial foods like diet soda or even beer will have a negative effect on your Test levels.

The optimum setup for your best test levels is a 100% whole food diet, solid deep sleep nightly, and daily consistent light to moderate intensity workouts. In real life this is very difficult to actually consistantly maintain, at least for myself.
I did a lot of testing on myself when i thought i had some low test problem, but basically the conclusion I came to is your Test levels can be dramatically different from one day to another. 10-20% difference easy, sometimes 50% in extreme cases.

Just work with what you have and avoid crashes throughout the day.

For example in the morning your test levels are the highest, and then your t/e ratio falls as the day goes by. It can be extremely low by say 8PM and your estrogen can be really high at night because all your test has aromatized into estrogen, but by next morning it should be back to normal.

Then lots of external things we consume can really effect your intra-day test levels. For example too much glucose at one time can crash your test levels, soda, alcohol, etc.

Having shitty sleep as a result of caffiene can result in bad next day test levels.

Walking 1 mile is as effective at lowering blood sugar as metrofrmin, at least that is what I have read.

I think for you, number one priority is to drop all drugs you are on, including Xyrem as soon as possible. Then do only clomid to fix your testosterone levels, if you can. Having good test levels should get you to sleep extremely well.

I think you should walk a lot plus clomid to keep your test levels up. Hopefully this can fix your blood sugar issues.
Clomid and arimidex combo is good too, but focus mainly on using clomid and not arimidex. Arimidex will fuck you up mentally much more then clomid.
Also Arimidex is very bad for bone density, don't mess around with Aromatase inhibitors if you don't have to. You can eat Calcium D glucurate pills or Brocolli/cabbage to flush estrogen out of your system (natural anti estrogen ).

You clearly need to get your high blood sugar fixed up, so I would use clomid to help you lose weight by doing lots of cardio. Way more then only 60 minutes per day. That's nothing. I know too much cardio will lower test, but with clomid on hand you don't have to worry about this as much. Clomid should keep your test levels up high even if you are over training.


Injecting test will most likely directly fix your metabolic problems much faster, (especially the elevated glucose issue) but then you will be stuck with the responsibilty of being on test forever.

I also tested my T several times before all the drugs I was prescribed and it ranged from 125 to 400 for Total T. I was getting mood swings and depression at those levels... Not only that, but I also have MPS - Myofascial Pain Syndrome (trigger points all around my body), 5 disc herniations (some with stenosis), and some "fibromyalgia"-type pain. Clomid + Arimidex reduced my pain levels more so than any pain killer I ever tried. Eating healthy, getting sleep, and light, etc. doesn't work for everyone... I had Mumps as a child, which can permanently mess up a guy's testosterone levels and I was kicked in the nuts like 3 times (I didn't know you can't tell American women that they are getting fat...). The bottom line questions is what's more toxic on my body: tiagabine + baclofen + gabapentin + hydroxyzine + omeprazole + dextroamphetamine + lamotrigine + narcotics + acetaminophen + GHB OR Clomid + Arimidex + GHB? I will eventually stop GHB when my GABA A withdrawal ends and I can spend the night without severe itching all over my body.

Doing more than 1hr cardio per day? No way - I am already exhausted, but its likely due to my benzo-like withdrawal because before I stopped all those drugs and was prescribed Clomid, I could spend 3-4 hours at the gym without getting tired. Now I can do 90 minutes tops, but as my withdrawal improves, I can slowly increase weight lifting and cardio by a 5-10 minutes per 1-2 weeks.