Opioids Best first gen antihistamine for opioid potentiation?

[evo4ever]

Hello all.

Currently I'm prescribed 120mg of Oxycodone IR daily and I wanna know which is the most effective first generation sedating antihistamine for making my Oxy feel a little stronger? I've ordered 3 different first gen antihistamines from 3 separate legit online pharmacies. I've got Promethazine 25mg, Diphenhydramine 50mg, and Chlorphenamine 4mg on their way to me. I'm gonna experiment with them to see which one gets me higher but with a little input from u guys as well. I'm gonna try and get my hands on a pack of Hydroxyzine too but I think it's prescription only now.

 

[HoldBack]

Idk if anyone will have tried enough antihistamines to really give you a good answer here.

I’d recommend promethazine just for ease to acquire and good tolerability.

Hydroxyzine is a great drug, however not for your purpose. Good for anxiety control and sleep.

I find diphenhydramine to have a nasty hangover and makes me restless.

Chlorphenine makes me feel unpleasantly drugged. There’s no “right” dose for it. Like I feel it’s too much or I don’t hardly feel it at all.