RCs A recup of my discoveries over the past.

[Gaffy]

Can't insert quotes...

 

[Gaffy]

Here I'll be posting my best inventions, selected for their binding profiles.

It'll take some time to finish this thread (if I ever do as I've litterally thousands of chemicals to sort out and run through, and test with the SAR machine), but I'll post what I think deserves to be posted.

We'll start with Ketamine and Ephenidine analogs I've invented, and switch to BTCP analogs which will permit us to switch to DRIs: (And from there it'll be pretty random, as I can't classify all my compounds)
Ketamine
PCP
Ephenidine


Seven ringed Ketamine,
CycloHeptylKetamine : C1(C(CCCCC1)=O)(C2=CC=CC=C2)N(C)[H]

Seven ringed Methoxetamine,
CycloHeptylMethoxetamine: C1C(C(CCCC1)(C2=CC=CC(=C2)OC)NCC)=O

Adding a benzene group to the cycloheptyl:
3-MeO-PCPy with a PhenylCycloHEptyl ring: C1CC(CCC2=C1C=CC=C2)(C3=CC=CC(=C3)OC)N4CCCC4

a little extra


(With very interesting SARs)
MorphoKetamine: ClC1=C(C=CC=C1)C1NCCOC1C1=CC=CC=C1

PCP with a N-PhenylPiperazine
PCPP: C1=CC=C(C=C1)N2CCN(CC2)C3(CCCCC3)C4=CC=CC=C4

BTCPP, BTCP with a phenylpiperazine
BTCPP: C1=CC=C(C=C1)N2CCN(CC2)C3(CCCCC3)C5=CC4=CC=CC=C4S5

Three analogs between Ephenidine and BTCP:

BTPhenEthylPiperidine : C(C(N1CCCCC1)C1=CC2=C(S1)C=CC=C2)C1=CC=CC=C1

BTPhenEthylPyrrolidine: C12=C(C=CC=C1)SC(=C2)C(CC3=CC=CC=C3)N4CCCC4

BTBKPhenEthylEthylamine: C12=C(C=CC=C1)SC(=C2)C(C(C3=CC=CC=C3)=O)N(CC)[H]

The morpholine analog of ketamine applied to BTCP:
MorphoBTCE: C1COC(C(N1)C1=CC2=C(S1)C=CC=C2)C1=CC=CC=C1

Mono-methylated alpha-phenylated tryptamine, a SNDRI that stands out:
N-Methyl-Alpha-Phenyl-Tryptamine: C1=CC=CC2=C1C(=C[N]2)CC(C3=CC=CC=C3)NC

Its N-Pyrrolidino analog

5-MeO-AMT
C1(=CC=C2C(=C1)C(=C[N]2)CC(N([H])[H])C)O

Cocaïne analogs: probably my best inventions

I Don't know what to call these, but they're wonderously promising
COC(=O)C(CC1=CC=CC=C1)C1CCCN1

The N-Methyl, even more promising
C1(=CC=CC=C1)CC(C(=O)OC)C2CCCN2C

The local anaesthetic version, it's got high HERG activity:
C1=CC=CC=C1C(OCC(C(OC)=O)C2CCCN2[H])=O

The N-Methyl version, with even more HERG activity, which makes it cardiotoxic
COC(=O)C(COC(=O)C1=CC=CC=C1)C1CCCN1C

An outstanding one,both SNDRI and MOR (!)

N'-N-Methyl version

2-FA Light
C1(=CC=CC=C1OC2CCN(CC2)[H])F

4-MethylMethylphenidate N-pyrrolidine analog
C1=CC=CC=C1C(C(N2CCCC2)=O)C3CCCCN3[H]

PVP Methylphenidate: Surprisingly good
C1=CC=CC=C1C(C2CCCC3CCCN23)C(OC)=O

N-pyrrolidino Version


3-MeO-PhenEtrazine
C1=C(C=CC=C1C2C(CC)N(CCO2)[H])OC

CyclopentylEthylCathinone
CCNC(C1CCCC1)C(=O)C1=CC=CC=C1

Two Ketobemidone variants, go guess how I guessed

BTKETO1
C1=CC=C2C(=C1)C=C(S2)C3(CCN(CC3)C)CN4CCCC4

BTKETO2
C1=CC=C2C(=C1)C=C(S2)C3(CCN(CC3)C)C(N4CCCC4)=O

Should be opioïd, is Dopaminergic and Opioïd sigma active:
C2(CC(CC1=CC=CC=C1)N(CC2)[H])(C(=O)CC)C3=CC=CC=C3

Ketobemidone analog:
C1(C(CN(CC1)C)=O)(C(=O)CC)C2=CC(=CC=C2)O[H]

Chlorphenamine derived Antihistaminergic Psychedelics, or chillaxed tripping!

5-Meo one
C1=C(C=CC2=C1C(=C3C=CC=C[N]23)CCN(C)C)O

Chlorphenamine inspired
C1=CC(=CC2=C1C(=C3C=CC=C[N]23)CCN(C)C)Cl

5-Meo DIPT one
C1=C(C=CC2=C1C(=C3C=CC=

 

[Gaffy]

I meant the picture I committed to naming GAFFY in the Name-A-Molecule thread ^^ This one:

A-AVP

Alpha-AziridineValeroPhenone


Edit:I just realised the difference between pyrrolydine and pyridine.. I will update that asap!

Done

Ethyl 2-(Piperidino)-1-3'-hydroxyphenylcyclohex-3-ene-1-carboxylate

I also like this one. Can't post STP results but it seems lile a winner.

8-Ethyl-7-PHenYLoctahydrOIndoliziNE

EPHYLONE

Dopaminergic cannabinoid, shares androgen and estrogen liability. Should be euphoric.

SwissTargetPrediction

swisstargetprediction.ch

Now let'd take the above and make it a bit more expensive, to get pretty much similar effects.. As of yet, a gold holding dopamine agonist etc etc

Just a little example of the many possibilitys

Or

 

[jhjhsdi]

@Gaffy ...Wowzers
How do you just 'invent' analogs?
Do you mean you've actually made these in a lab? Or just drawn the structures?
Impressive, either way!
I thought you were just a guy who liked to inject RCs I didnt know you were a scientist lol