I am not sure if that is a fair comparison as the base tryptamine will have a greater impact than the subsitution on the effect profile of the substance?
Good to know though and I have heard 4-aco-dipt is less likely to produce tremors.
Personally more interested in 4-ho-mipt and aco-mipt comparisons, from what I understand the hydroxy has less side effects.
I'm pretty sure I have read some reports on erowid of 4-AcO-DiPT involving leg tremors and weird uncomfortable body energy... seems a lot of us (that does not exclude me by the way) are going on the anecdotal evidence that we happen to have gathered, i.e. what we heard that incidentally happened, but does not really offer statistical relevance whatsoever.
By the first remark/sentence I assume you mean that the N-substitution (i.e. whether it is 4-xx-DET or 4-xx-MiPT etc) might mostly determine the side-effects profile, and not whether it is the 4-HO or an ester like 4-AcO, 4-PO, or 4-Pro etc.
That is an assumption we have no proof of as far as I can tell, and I started this meaning to try and find out more.
After making the thread I realized that mushrooms can also cause pretty weird side-effects like jelly legs, brain zaps and feeling as if one is wet / has wetted him or herself... I wouldn't be surprised if tremors are also very possible with them, I just never happened to hear about it explicitly or that I can recall.
Many people insist that 4-HO tryptamines and their corresponding 4-AcO esters are not simply interchangeable, but 4-AcO's are considerably more stable. Wouldn't it be pretty valuable to the scene if we knew how much of this is in our heads as biases, assumptions, etc?
If I were more free to do so, I would ask a friend to help me with a blind trial to see if I can differentiate between a 4-HO trypt and the corresponding 4-AcO in equimolar dosages, and if there would be subjective differences, to write down which ones.
Imagine if a few people would do such experiments it would perhaps offer convincing info...
And yeah disclosure: my suspicion is also that hydroxies have less side-effects... although acetoxies have smoother comeups and comedowns, also hydroxies seem to be able to be a bit more menacing and in your face visual probably because of the immediate action and straight-forward kinetics in the body.