Perhaps look into oral Methadone tablets (scripted a 100 tablet sealed bottle) ….due to its very long half life, a full mu-agonist and NMDA antagonist properties, it’s very suitable for long term chronic pain.
….not just for Heroin addiction
It’s a prominent long acting, potent opioid narcotic analgesic that any family doctor can prescribe as an analgesic.
I too was on Oxy-IR 5mg x 6 daily and then Dilaudid 2mg x 4 daily /Hydromorphone 9mg XR x 2 daily, but short acting opioids are best suited for short term pain management (like a broken leg, surgery, etc)
Hydromorphone (Dilaudid) although a very potent opioid, taken orally has a piss poor bioavailability. Roughly 70% of the oral dose is destroyed by first pass metabolism (your liver). Dilaudid is most suitable for hospital administration via IV/IM injections, bypassing the liver and rapidly penetrating the BBB with 100% bioavailability
Oral Methadone has excellent bioavailability of approximately 80%, and increases when taken “chronically” as it builds up after 4-7 days due to it 24h half life, becoming more potent after daily usage for weeks+. However, it’s true potent analgesic pain killing properties only last 5-8 hours of duration……but many patients are held just fine with a single daily dosage.
I have been on Methadone 80mg daily for 10+ years, started from 30mg and slowly increased until optimal dose achieved.
For yourself, doctor could start you on 5mg tablet in morning, and another after dinner…..then slowly increased once a week until your pain in under control and you’re not impaired, dizzy, sleepy, etc. research it and be aware of any DDI and not combined with any other CNS depressants such as benzodiazepine which can cause slow breathing and accidental overdose
Your doctor might be impressed with your knowledge of DDI regarding Methadone, and emphasis on safety….while suggesting starting at the lowest dose 5mg tablets and each week or 2 weeks, doc can safely increase
Speak to your doctor if you wanna go that route…..Fent I’ve never tried, now highly stigmatized by massive illicit supply and O.D. numbers. Dilaudid HM is an amazing potent classic opioid very similar to Diamorphine (Heroin) in potency and subjective
Dilaudid (Hydromorphone) all the way ……f@ck fent
Some individuals who want to significantly increase the bioavailability of HM without crossing the scary line of injecting oral tablets (which can result in relatively hazardous harm, and many health complications can occur) ….they choose the safer route of dissolving pulverized powder from crushed tablets in room temp bottled water, drawing up in oral syringe (without needle) and slowly administer HM solution into rectum while laying on side in privacy of your bedroom or locked washroom if people in house
Just 1/2 to 3/4 the length of your pinki finger inside and slowly push plunger and lay there for a few min to absorb a bit.
I personally have never administered this way, but many have described it, and has Excellent bioavailability, greater absorption, faster onset, and most importantly…..bypassing first pass metabolism so your liver won’t destroy 70% of the oral dose you would’ve taken
I totally would have done this btw ….but current on Methadone 80mg daily, so HM would have zero effect on me. After 40mg of Methadone daily for several weeks/months all the mu-opioid receptors in your CNS are completely saturated with the super long 24h half-life Methadone that inhibits other opioid agonists from binding / taking a noticeable effect
While on Methadone 60mg for months…..I took 3 & 4 tablets of genuine OxyContin 80mg and felt F@CK ALL. Absolutely nothing. I’m on 80mg now.
Oxycodone was the most euphoric & pleasurable in addition to being an amazingly effect & potent opioid analgesic
Hydromorphone was VERY potent and super effective opioid analgesic, but being significantly more sedating, and definitely less euphoric ecstasy compared with oral Oxycodone.
That being said, Dilaudid (Hydromorphone) is a HIGHLY respected, highly desirable, gold standard Heavy Hitter with no ceiling dose and can eliminate even the most extreme pain, given the required mg dosage. Pharmaceutical Dilaudid HP Fort solution for IV/IM/SC injection (100mg/per ml) in a cute tiny little 15ml glass vial with red label Sandoz Pharmaceuticals ….google it to see the pic. It’s so beautiful lol.
feelings, but short acting and best used as a pharmaceutical injectable solution.
I suggest oral Methadone for long term chronic pain conditions, requiring a long acting potent opioid with a long 24h half life, suitable for once a day administration for some people.
Best o