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Benzos RC benzo recommendations

fugme said:
Diclazepam (2'-chlorodiazepam) has been recommended a lot on the internet for tapering.
What about Ro5-4864 (4'-chlorodiazepam) or gidazepam/desalkylgidazepam - has anyone tried them, for tapering purposes or otherwise? i'd greatly appreciate any input!
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OK diclazepam was actually designed as 'the methadone of benzos' with a half-life of 42 hours and a half-life of active metabolites (delorazepam, lormetazepam & lorazepam) of about 9 days.

It's quite reasonable to dose diclazepam once a day. It is a high-affinity ligand. For that reason, if one can get down to 2-4mg/day, swapping for 20-40mg of diazepam and reducing is likely the best option.

I was taking 24mg/day of diclazepam for over a year and the doctor had to give me 360mg of diazepam to stop the severe symptoms. It took me a year to stop and 10 years later diazepam still has no effect on me so I think the 'kindling effect' extents to permanent alteration of the receptor.

Oh, but another tactic is to swap to clobazam (a 1,5-benzodiazepine). It binds at different sites so in practice it just reduces anxiety and increases seizure threshold. You will still have a LOT of anxiety (clobazam seems to have a ceiling) but it's possible to go from a huge habit to nothing (in practical terms) in a way that is quite safe. But of course, ask a doctor.
 
I just ordered some fluclotizolam to try.

Recently I tried deschloroetizolam and I found that similar to etizolam, however it is much less potent.

I've been wanting to try rilmazafone which is a water soluble prodrug to rilmazolam.

I recently had tons of Ativan in the hospital and that was enjoyable.
 
fugme said:
Diclazepam (2'-chlorodiazepam) has been recommended a lot on the internet for tapering.
What about Ro5-4864 (4'-chlorodiazepam) or gidazepam/desalkylgidazepam or pagoclone - has anyone tried them, for tapering purposes or otherwise? i'd greatly appreciate any input!
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Wiki sez gidazepam can be a treatment for giddieness. Sounds like a very serious drug.
 
Yeah but a lot of drugs can be used for different purposes / off-label. It has a very long half-life so it could be useful for tapering and stopping benzo addiction.
 
It's a shame that the ability of Chinese chemists is so limited. I have read over and over that brotizolam is by far and away the most potent benzodiazepine. I mean, active at ⅛ mg (0.0125 mg)!

Borrowing some tricks I discovered (to stop metabolism), it would be possible to make an analogue that might not be QUITE as potent (I guess active at ¼mg (0.25mg) or so, it WOULD have a duration of 6 hours or so. It's also the basis for my pypeyzolam (alcohol mimic) but it does require a lot of steps

I guess what ALL the mad people REALLY want to know is that zolazepam (Flupyrazapon) is EASILY the fastest acting. It's water-soluble and if you snort 5-10mg, you better do so while sat down or you will fall down.
 
Interesting note about using a solvent for benzos (and other drugs). I use a mixture of alcohols, averaging around 60-70% so i can do volumetric dosing. This way they get absorbed so rapidly i can feel them in 10 minutes. It also works great if your stomach is full and doesn't prolong the absorption and still hits you fully. Also great if you need a nap ASAP or you awoke in the middle of then night and can't go back to sleep - measuring the powder (incorrectly) can lead to serious inebriation / anterograde amnesia the following morning and volumetric dosing helps a lot.
 
fugme said:
Interesting note about using a solvent for benzos (and other drugs). I use a mixture of alcohols, averaging around 60-70% so i can do volumetric dosing. This way they get absorbed so rapidly i can feel them in 10 minutes. It also works great if your stomach is full and doesn't prolong the absorption and still hits you fully. Also great if you need a nap ASAP or you awoke in the middle of then night and can't go back to sleep - measuring the powder (incorrectly) can lead to serious inebriation / anterograde amnesia the following morning and volumetric dosing helps a lot.
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I would imagine alcohol is a great carrier. Could be useful for me. However my wife can not drink so I have to investigate PG as a carrier for when she needs. I guess i have to scour BL on the protocol and process for that.
 
Unless you have massive tolerance and require huge dosages, you and your wife will be ingesting less than 4ml of alcohol (absurdly small amount). I usually dissolve 2mg of benzo for every 1ml of alcohol, so every milliliter syringe carries 2mg of benzo.
 
Good to know fugme. I am for sure going to give that a shot. I have Everclear here. Almost 100 proof. I guess that would work.
 
JackARoe said:
I would imagine alcohol is a great carrier. Could be useful for me. However my wife can not drink so I have to investigate PG as a carrier for when she needs. I guess i have to scour BL on the protocol and process for that.
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Everclear (95% ethanol) works amazing for benzo solutions. I can get etizolam down to 1mg/0.2mL, same with 3-ho-phenazepam. PG is a lot worse of a carrier, you have to heat it and agitate it a lot to get even etizolam to dissolve... not so with ethanol, I shake it once, leave it an hour, shake it again, and it's ready to consume.
 
Everclear is basically perfect dude. Wish i had it. I would, however keep the vials tight and in the fridge, just so it doesn't possibly evaporate slowly at room temperature.
 
fugme said:
I would, however keep the vials tight and in the fridge, just so it doesn't possibly evaporate slowly at room temperature.
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IME this doesn't occur. I've left etizolam in Everclear for months at room temp and not seen a drop in the volume inside the vial. I use amber vials with sealed plastic caps on top from a major glass distributor.
 
I use the same kind of vials, they also have this rubber-plasticy inserts you put in before screwing on the plastic cap. I just don't want to take any chances for some very potent drugs that might be sitting there for a year or more. Couple of miligrams difference for etizolam wouldn't cause any problems, but there are drugs that are far stronger and could potentially cause some troubles.
 
JackARoe said:
Good to know fugme. I am for sure going to give that a shot. I have Everclear here. Almost 100 proof. I guess that would work.
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Here's how i do it. I have 20ml vials, which i usually fill several at once, to avoid the hassle of refilling often.

1. I use bigger, 20ml syringe (very cheap) to draw in the alcohol and fill every vial and sealing them.
2. Then i measure 40mg of etizolam and with help of funnel or aluminum foil carefully pour in the powder.
3. I leave them at room temperature for several hours tops and shake the vials in between.
4. I always put a white sticker on every vial stating:
ETIZOLAM​
20ml ---> 40mg​
1ml ---> 2mg​
​
5. I use 1ml syringe (the smallest on in pharmacy, also very cheap). 1ml of solution is 2mg of benzo, 0.5ml of syringe is logically 1mg. Then i mix it with water, swirl around a bit and drink it. then i pour in some more water, swirl it around and drink again.
 
^ Info saved! So 20 ml of alcohol to 40 mgs of etizolam. Seems easy enough. For my use I am going to use this method. I just did not know the ration of carrier to etizolam/fluclotizolam. Both seem similar in strength so should work for both.
 
Yeah. You can of course use bigger vials and fit more alcohol / benzos, you could also play with ratios like @Cream Gravy? I used to do the same with fluclotizolam (until i ran out) and then just adjust the intake. Like 3mg of fluclotizolam (1,5ml) or 4mg of etizolam (2ml). You can do this with practically any potent benzo that isn't measured in few dozens of milligrams and needs careful volumetric dosing.
 
Beautiful, this is the thread people should go to if they are making a solution. :) I got all I need to know now. I probably will make it a little lighter but based off of the same math. 1 mgs of etiz works fine. I only take 2 mgs about 12 hours after an acid trip. I find 2 mgs damn strong.

I think I am sensitive to the amnesia effects. I mean I can remember things but if I am binge watching a tv show and even do 1 mgs of etizolam or 10 mgs of diazepam I have to rewatch the episodes. Not that I will ever try and find out but I wonder if this effect goes away with tolerance or using medically. Then when I rewatch the episodes I remember. So really benzos seem to affect recall more than memory.
 
I suspect that the effects of etizolam are not reliable with quite, quite different effects on different people.

The other class of agent people need to be REALLY careful with is the opioids. I am shocked that BDPC and it's analogues are seemingly on the market. Agents over 500 xM should be classed as chemical weapons, such is their ability to cause death.
 
Feretile said:
I suspect that the effects of etizolam are not reliable with quite, quite different effects on different people.
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I believe you are correct. Even with me at different times seemed different, like from the same batch. One time sleepy, another time it can make me bouncy and dysphoric. One time I was agitated to where all I could do was sleep. Most of the time it does not do that.

Where as diazepam always does the same thing to me. Calm, relaxed and never bounciness.
 
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