I'm one of those few who do benefit from higher doses than 20g at times. I didn't need doses above about 10g for full effects prior to utilizing it for post operative pain, which caused my doses to escalate out of control rapidly with regimented, 3x daily dosing. I peaked at a out 25g/3x daily then, but had worked hard to get down to 10g in the morning and 16g at night until around 2 weeks ago, when I was put on montelukast.
Montelukast seriously fucked up my metabolism of kratom, alprazolam, and levetiracetam. This last week I was taking 30g/4x daily during my metabolic mishap. A dose that high, even at the height of my use prior to the montelukast incident would have left me fairly ill; with my metabolism screwed up, I was taking 120g daily just to get to normal!!
As of today I'm back down to 15g in the morning, 15 in the afternoon, and 30g at night with my plan being to slowly taper out my afternoon dose removing between .5 and 1g a day, then stabilize at 15g in the morning and 30g at night prior to starting , again, more slowly reducing my morning dose before lowering my nightly dose as it's the most important one for my sleep.
I intend to get back to the point where I am no longer physically dependent on daily dosing, like I was prior to my surgery. I do not intend to stop using it altogether, but I'd like to be able to use it once or twice a week as need for pain.
I dont know if chipping will work better with kratom than other opoids, but I'll find out eventually. I want to get in a 30-60 day period of no use at all before trying it again. I'm not sure how long it'll take me to taper down to nothing before I can get a break in, but I'm not going to stop tapering until I do.
I know my situation is far from the normal kratom use, but i know of at least a handful of BLers taking upwards of 50g daily without any real side effects outside of constipation. I never got any of the side effects that other experience; nausea was only an issue if I seriously overshot my dose, I never got the headaches, tremors or stimulation preventing me from sleeping with the exception of high doses of White Dragon. That's the only strain I've tried that's genuinely stimulating, it's my favorite for morning use.