You can be skeptical all you like. I have seen enough things through the dmt molecule to believe that there is a purpose behind it. What that is i dont know.
Answer this. How did the shaman in the Amazon identify two different plants that by themselves do fuck all but when combined produce something as amazing as Aya. Out of all the plants in the Amazon they found those two combined to create magic. Just another extraordinary facet of the dmt mystery.
I used to think that, but the Caapi / MAOI containing part is psychoactive on its own, and so much time passed for them on such an area to figure it out - not that much else to do - which plants can be added to it... it's a typical hyper-open-minded argument, and usually the skeptical counterargument is that unlikely things are eventually likely to happen, also applying to the chance of alien life paradox or synchronicity - it's maths that's not quite that intuitive to people just like people expect randomness to be close to an even distribution which in reality things tend to be clumped a la "bad luck always comes in pairs" or at least paraphrasing translation of a saying in my country.
People are terrible at statistics, it does not remotely compare to our feelings about things and our fallacies.
If there are actual arguments and claims that have so much bearing that they actually resist explanations like that, then it would get interesting. I think an Amazon medicine man / shaman could be able to sense a hell of a lot that we can't, but I believe the cues are still there, and were there before even if acuity gets amplified... so it's natural phenomenon and nothing too esoteric.
Esoteric theories are the least elegant of all. Resist being so impressed that you ignore the doubtful position.. I don't close myself to alternative possibilities, but I don't believe in anything just because it's impressive.
Magic is pretty much science that is not yet elucidated and so far virtually everything has followed this rule - many things are disenchanted over time.
How reasonable is it to put much faith in the margin that is not yet elucidated, without proper evidence? I mean there is not even anecdotal evidence that supports ideas of the kind.
We can ask ourselves what is more important: to know the truth or to believe in something that makes us feel better... of course not everything can exactly be divided this way, but still it applies to some of these matters...
Since rational explanations don't drag such vagueness into it , not based on proven principles I think the burden of proof lies with the esoteric.