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Guide to Antibiotics and MDMA

Hi guys.
Want to ask about antibiotics called levofloxacin. Just got the prescription and already took 2 of them in the first day.
The problem is I got this big party tomorrow and is it safe to take it with mdma?

Or should I stop consume the antibiotics just for tomorrow and continue it after?

Any enlightenment would be greatly appreciated.

Thanks
 
Hi, I took 1000mg of Azithromycin earlier today as a 1 off for an infection and won't be taking any more, however tomorrow night I am going out for the last time before moving country and therefore I want to roll as it's the last night with some close mates and it's been planned for ages..

I saw in this thread that it should be okay, however I have seen on other websites that it can be dangerous.

Does anyone have any advice or personal experience?
 
Hey so I'm having a situation that I need help with. Over the weekend I got a stress induced/hormonal Imbalance bacterial infection in my mouth. I was givin 150mg of clarithromycin and I was directed to take it 4 times a day. It is now Tuesday so I've been taking the antibiotic for goin on 4 days now. I am not one that takes mdma too often but I have been planning on going to this rave that's going on this upcoming Saturday night and I planned on taking 4 points. I understand that clarithromycin is one of those antibiotics that breaks down the enzymes in mdma or something? So, I will have only 2 pills left when I reach Saturday morning and I don't know if I should stop taking the last two pills and allow my system 15-20 hours to pass the clarithromycin before I take the mdma or if it is safe enough to roll while on it. Since I'm practically done with my instructed dosage I thought stopping two pills early would be the smarter thing to do. I want your guys advice. Don't give me bad vibes, I've had plenty of friends tell me that they have rolled on antibiotics so I dont I won't die or anything. Just give me tips on what to do that everything goes smoothly. Im a bit of a worry wart. Thanks :)

By the way, the pain and swelling stopped after just a night of taking the clarithromycin. So it's not like I'm still showing symtoms. I get that my body might still be fighting off the infection but I just thought that may be useful information. I would love responses from people who rolled while on clarithromycin specifically if at all possible. :)
 
somebody i know was prescribed a 7 day course of liquid Clarithromycin, he then went out a few days into the course and took 1/2 gram of MDMA, he rolled fine as he normally would and there were no major differences, other than the fact that it took considerably longer for him to come up..
 
Any suggestions regarding taking a pill while on clarithromycin? (aka klacid)
Started my dose today which is a 500mg tab once a day. The infection (chest) should get a lot better by this coming Monday (considering taking it Monday night). If the risk of taking it is low then I will only take half a
 
Any suggestions regarding taking a pill while on clarithromycin? (aka klacid)
Started my dose today which is a 500mg tab once a day. The infection (chest) should get a lot better by this coming Monday (considering taking it Monday night). If the risk of taking it is low then I may only take half a pill.

All replys are greatly appreciated!
 
Posted this as a separate thread, but I think this Guide might allow me to get the most helpful answers -
Curious about the interactions between MDMA and Doxycycline. If one were to be on 200 MG doxycycline, what would the effects be with MDMA? I understand that the effects of the MDMA are potentiated because it's breakdown is slowed by the fact that doxycycline inhibits the enzyme CYP3A4. As such, it could be dangerous because MDMA would not be broken down fast enough. However, I'm curious if anyone would like to expound upon this in more detail. Doing some research has shown that this could also be neuroprotective to a certain degree. Thus, could it actually be possible that MDMA (in half dose, say) in combination with doxycycline could have the same effect as normal dose, but with added neuroprotection?

Additionally, does anyone know on the reverse side, how the use of MDMA might affect the efficacy of doxycycline? I mention the use case of doxycycline here has being taken for acne, not for treating a short-term infection.

Thank you alll!
 
I am currently on a prescribed drug called ramipril it LOWERS/CONTROLS blood pressure as mine seemed to be slightly high. I take it daily (10mg per day) I am goin to a festival soon for a few days and wanted to take MDMA, not loads, just 1g over the coarse of 4 days, little bits at a time. My friends did this last year and had the times of their lives. I have taken it before, when on 2.5mg ramipril, and when on no medication/antibiotics and had no ill affects. Would you say it was ok to take? All feedback is appreciated. Thanks
 
The dangerous thing is that many bacteria are dying and releasing their poisonous byproducts in your system (overflow). This is one of the reasons, next to a possible superinfection, why you shouldn't exercise during and one week after antibiotic therapy. MDMA is an aphetamine and pressures your cardiovascular system and your heart, which can lead (pretty much worst case scenario) to a heart infection or directly damage to your heart. The damage done to your body is often times invisible to you. I wouldn't do it.

@ Leebo, wrong thread and you either take the risk by taking it or you don't do it, simply as that. Nobody knows what is going to happen in your system/ with you.
 
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Thanks mb-909, pretty new to this site? Is there a Health Q & R forum? If so how do I find it?
 
Leebo said:
Thanks mb-909, pretty new to this site? Is there a Health Q & R forum? If so how do I find it?
Click to expand...
1g over 4 days. SMH. That's too much!! 150-200mg should be the max you ingest on one setting and waiting atleast 1-3 months between rolls is a good rule to follow. But taking 1000mg over 4 days. Bad idea
 
charles23 said:
Posted this as a separate thread, but I think this Guide might allow me to get the most helpful answers -
Curious about the interactions between MDMA and Doxycycline. If one were to be on 200 MG doxycycline, what would the effects be with MDMA? I understand that the effects of the MDMA are potentiated because it's breakdown is slowed by the fact that doxycycline inhibits the enzyme CYP3A4. As such, it could be dangerous because MDMA would not be broken down fast enough. However, I'm curious if anyone would like to expound upon this in more detail. Doing some research has shown that this could also be neuroprotective to a certain degree. Thus, could it actually be possible that MDMA (in half dose, say) in combination with doxycycline could have the same effect as normal dose, but with added neuroprotection?

Additionally, does anyone know on the reverse side, how the use of MDMA might affect the efficacy of doxycycline? I mention the use case of doxycycline here has being taken for acne, not for treating a short-term infection.

Thank you alll!
Click to expand...

from my research noone knows. There are some who have used doxycycline and mdma together and said the roll was better and some say it didnt seem to effect . do what you think is best
 
I am currently taking Metronidazole (flagyl) is it safe to roll while taking this?
 
Since this was written there have been several papers on minocycline-MDMA interactions in animals, suggesting minocycline will alter MDMA effects, but not necessarily in a dangerous way. Also, I would warn about linezolid, which has some MAOI ability and has been known to cause serotonin syndrome on its own.

Even if a combination of antibiotic and MDMA seems low risk, I agree with others that it is unwise to take MDMA when you have an active infection or illness, as MDMA affects the immune response (the Anne is true of alcohol).
 
I was on doxycycline 200mg a day for a week. I did not stop my antibiotics as this was a very last minute concert. I took 1 cap that night. Other than having a bit stronger of a come up and sweating more than usual I didn't notice anything negative. Although as some mentioned I did hallucinate a little bit, not that was exactly a bad thing. This was all a few weeks ago, the antibiotics did their job fine, however I wasn't taking them for any real physical illness so I would definitely listen to your own body <3
 
So I was prescribed 5 days of Zithromax to treat bronchitis that I had, I also had strep throat, but they messed up and I did not get my 10 day prescription of amoxicillan for that until 4 days later. So I finished the 5 days of zithromax and just started the amoxicillan, but i have a concert in 7 days I have E I want to roll for. My strep already feels like it is gone, the zithromax must have helped with that. So if I take a break the day before and dont take any amox. on friday and roll that night, and then resume the meds after that will i be fine? I think the strep bacteria should all be dead by then, and I dont want to risk taking the XTC at the same time as the amox.
 
I'm not sure about mdma because I haven't taken it while on antiobiotics but I tested positive for MRSA 4 years ago and so far had 5 infections since then and (I know this sounds rediculously stupid and unhealthy) I was smoking crystal while taking sulfa/bactrim and doxycycline. I didn't notice any scary reactions so I don't see how mdma could be more of a risk than speed. They still worked perfectly fine and killed the infection pretty fast every time so the meth didn't seem to interfere at all. I've also smoked plenty of weed while on antibiotics as well but imo weed is completely safe and can be used with anything.

I don't even have a clue how or why I ended up with MRSA because I don't have any of the risk factors. Maybe the years of meth use fucked up my immune system? My roa of choice is the pipe (or bong) and never touched needles in my life. I also don't know anybody else who has it so it's a complete mystery how I contracted it. I'm not a dirty person either. It sucks cuz I feel like it's going to keep coming back and the skin infections/boils are really fucking painful and seem to just randomly pop up out of nowhere. It also takes weeks to heal and at least a year for the scars to go away.

Anyways the only reason why I continued to use meth while being sick and on antibiotics is because I'm addicted to it and most likely would of felt even worse if I stopped cold turkey and added withdrawal to the mix. I used to take a lot of E and Molly but this was a long time ago before the mrsa and I never used mama more more than twice a week so I don't recall being on antibiotics during any of those times. Everyone's body handles drugs differently so it's hard to tell how they will affect someone else. It's better to be safe than sorry though that's for sure.
 
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hello everyone, i have been reading few times this forum but i have now registered and have a question. today is my last out of 3 days of antibiotic called Azithromycin and i plan taking a pill exactly a week after on friday late night. I see on this list that Azithromycin is theoretically safe but on another forum i read that it is STRONGLY DISADVISED to take mdma while taking Azithromycin. I have small number of bacteria in my urinary tract and i am generally healthy, i train every almost every day and i get sick 1 time a year or less so i am not worried about my infection that much. I am just worried how mdma works with azithromycin because it stays in system a little bit longer than other antibiotics. Please help :)
 
I honestly think its ok. The problem is azithromycin gets lumped in with other similar drugs like clarithromycin or erythromycin, both of which are rather strong inhibitors of the metabolism of other drugs, when it itself does not. Why did the other sites say not to take the two together?
 
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